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239797-09-2

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239797-09-2 Usage

General Description

2-[(4-Ethoxyphenyl)sulfonyl] propanoic acid ethyl ester is a chemical compound with the molecular formula C13H18O5S. It is an ester derivative of propanoic acid and belongs to the class of sulfonamide compounds. This chemical is commonly used as an intermediate in the synthesis of pharmaceutical and agrochemical products. It can also be employed as a building block in organic synthesis to create more complex compounds. Additionally, its sulfonyl group makes it a potential candidate for use as a pharmacological agent, such as in the development of new drugs. Overall, 2-[(4-ethoxyphenyl)sulfonyl] propanoic acid ethyl ester has a range of applications in the chemical and pharmaceutical industries due to its versatile properties.

Check Digit Verification of cas no

The CAS Registry Mumber 239797-09-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,9,7,9 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 239797-09:
(8*2)+(7*3)+(6*9)+(5*7)+(4*9)+(3*7)+(2*0)+(1*9)=192
192 % 10 = 2
So 239797-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O5S/c1-4-17-11-6-8-12(9-7-11)19(15,16)10(3)13(14)18-5-2/h6-10H,4-5H2,1-3H3

239797-09-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-(4-ethoxyphenyl)sulfonylpropanoate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:239797-09-2 SDS

239797-09-2Relevant articles and documents

Synthesis and structure - Activity relationship of α-sulfonylhydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis

Aranapakam, Venkatesan,Grosu, George T.,Davis, Jamie M.,Hu, Baihua,Ellingboe, John,Baker, Jannie L.,Skotnicki, Jerauld S.,Zask, Arie,DiJoseph, John F.,Sung, Amy,Sharr, Michele A.,Killar, Loran M.,Walter, Thomas,Jin, Guixian,Cowling, Rebecca

, p. 2361 - 2375 (2007/10/03)

The matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases that play a key role in both physiological and pathological tissue degradation. These enzymes are strictly regulated by endogenous inhibitors such as tissue inhibitors of

N-hydroxy-2-(Alkyl,Aryl or Heteroaryl sulfanyl, sulfinyl or sulfonyl) 3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

-

Page column 31, (2010/02/04)

Matrix metalloproteinases (MMps) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenases, stromelysins and gelatinases. TNF-α converting enzyme (TACE), a pro-inflammatory cytokine, catalyzes the formation of TNF-α from membrane bound TNF-α precursor protein. It is expected that small molecule inhibitors of MMPs and TACE therefore have the potential for treating a variety of disease states. The present invention provides low molecular weight, non-peptide inhibitors of matrix metalloproteinases (MMPs) and TNF-α converting enzyme (TACE) for the treatment of arthritis, tumor metastasis, tissue ulceration, abnormal wound healing, periodontal disease, bone disease, diabetes (insulin resistance) and HIV infection. The compounds of this invention are represented by the formula where R1, R2, R3and R4are described herein.

N-hdroxy-2-(alkyl, aryl, or heteroaryl, sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

-

, (2008/06/13)

Matrix metalloproteinases (MMPs) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenases, stromelysins and gelatinases. TNF-α converting enzyme (TACE), a pro-inflammatory cytokine, catalyzes the formation of TNF-α from membrane bound TNF-α precursor protein. It is expected that small molecule inhibitors of MMPs and TACE therefore have the potential for treating a variety of disease states. The present invention provides low molecular weight, non-peptide inhibitors of matrix metalloproteinases (MMPs) and TNF-α converting enzyme (TACE) for the treatment of arthritis, tumor metastasis, tissue ulceration, abnormal wound healing, periodontal disease, bone disease, diabetes (insulin resistance) and HIV infection having the formula wherein R2and R3form a heterocyclic ring and A is S, S(O), or S(O)2, and R1and R4are defined herein.

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