637-89-8

Usage

Chemical Properties

Clear colorless to light yellow solid or liquid

Uses

Different sources of media describe the Uses of 637-89-8 differently. You can refer to the following data:
1. 4-Mercaptophenol was used as a resin monomer in the study of the different gold nanocrystal core-resin shell structures.
2. 4-Mercaptophenol (MPH) has been used to study the adsorption of MPH on silver coated polystyrene nanospheres by time-dependent surface-enhanced Raman scattering (SERS) spectroscopy.4-Mercaptophenol may be used in the preparation of silylated monomer, which was employed for the synthesis of hyperbranched poly(ester-imide). 4-Mercaptophenol (H-4MP) reacts with metal tert-butoxides ([M(OBut)4]) to yield the following Group 4 phenoxy-thiols:[(HOBut)(4MP)3M(μ-4MP)]2, where M = Ti, Zr, Hf[(py)2M(4MP)], where M = Ti, Zr; py = pyridine[(py)(4MP)3Hf(μ-4MP)]2 4-Mercaptophenol may be used in the synthesis of the following:poly(ethersulfide)s via silylation followed by polycondensation with 2,6-dichloropyridine or 3,6-dichloropyridazine2,6-di-tertiarybutyl-4-mercaptophenol via Friedel-Craft′s alkylation with tert-butyl chloride in presence of a lewis acid

General Description

The density function theory calculations were performed to infer the IR and Raman spectra for 4-mercaptophenol molecule.

InChI:InChI=1/C6H6OS/c7-5-1-3-6(8)4-2-5/h1-4,7-8H/p-1

Upstream product

• 3774-52-5 4-thiocyanato-phenol 
• 2664-63-3 4,4'-Thiodiphenol 
• 140-89-6 potassium ethyl xanthogenate 
• 123-30-8 4-amino-phenol 
• 106-48-9 4-chloro-phenol 
• 3885-04-9 4-acetoxybenzenesulfonic acid sodium salt 
• 123-75-1 pyrrolidine 
• 243671-62-7 (Z)-2-((p-hydroxyphenyl)thio)-1-p-toluenesulfonylethylene 
• 7664-93-9 sulfuric acid 
• 4247-67-0 3,5-dibromo-4-hydroxy-benzenesulfonyl chloride 
• 2987-46-4 4-thiocyanatoaniline 
• 1029438-23-0 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol 
• 540-38-5 p-Iodophenol 
• 108-95-2 phenol 

Downstream Products

• 1073-72-9 4-hydroxythioanisole 
• 1195-46-6 4-(ethylthio)phenol 
• 95309-80-1 1-benzylsulfanyl-4-benzyloxy-benzene 
• 461-84-7 (4-trifluoromethylthio)phenol 
• 42302-04-5 (4-Hydroxy-phenylsulfanyl)-acetic acid 4-ethyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-tricyclo[5.4.3.0^1,8]tetradec-6-yl ester 
• 143745-64-6 4-<<2-(methylamino)ethyl>thio>phenol 
• 114568-48-8 4-(2-succinimidoethylthio)phenol 
• 63032-04-2 2-(p-hydroxyphenyl) thio-5-thiophenesulfonamide 
• 129700-49-8 6-(4-Hydroxy-phenylsulfanyl)-2,3-dihydro-benzo[1,4]dioxine-5,8-dione 
• 112254-15-6 4-hydroxyphenylsulfonylacetone 
• 27466-44-0 2,2-bis-(4-idrossifenilmercapto)propano 
• 62443-06-5 (4-Tetradecyloxy-phenylsulfanyl)-acetic acid 
• 30519-00-7 (4-Hydroxy-phenylsulfanyl)-acetic acid ethyl ester 
• 21101-58-6 4-hydroxy-2'-nitro-diphenyl-1,1'-disulphid 

Relevant academic research and scientific papers

SINGLE-STEP SYNTHESIS METHOD OF ARYL THIOL AND APPLICATION THEREOF

The present invention relates to a single-step synthesis method of aryl thiol, and more specifically, to a method of synthesizing aryl thiol in a single-step by making aryl halide react with alkane dithiol in the presence of a transition metal catalyst. According to the present invention, a single-step synthesis method using the transition metal catalyst, the synthesis method which is capable of synthesizing aryl thiol from aryl halide at a high yield, can be provided. Various aryl halides may be applied to the synthesis method. Further, the synthesis method has advantages that an easily usable reagent may be used, operations are simple, and reactions can be performed under mild conditions. In addition, the synthesized aryl thiol may be used in the synthesis of advanced molecules such as diaryl sulfides and benzothiophenes.COPYRIGHT KIPO 2017

A novel SERS nanoprobe for the ratiometric imaging of hydrogen peroxide in living cells

In the present study, a novel ratiometric SERS nanosensor via the assembly of 4-mercaptophenylboronic ester on the surface of gold nanorods has been developed and successfully applied in H2O2 imaging in living cells or cancer tissues.

A mild and selective protecting and reversed modification of thiols

One selective thiol-protecting study has been investigated for a wide range of thiols including general thiols and thiols containing multiple functional groups. The reactions of bromomaleimides and thiols under the mild condition afforded the protected products in excellent yields. The thiols can be recovered very quickly using dithiothreitol (DTT) under the mild condition.

Copper(II)-Catalyzed Single-Step Synthesis of Aryl Thiols from Aryl Halides and 1,2-Ethanedithiol

A highly efficient transition metal-catalyzed single-step synthesis of aryl thiols from aryl halides has been developed employing copper(II) catalyst and 1,2-ethanedithiol. The key features are use of readily available reagents, a simple operation, and relatively mild reaction conditions. This new protocol shows a broad substrate scope with excellent functional group compatibility. A variety of aryl thiols are directly prepared from aryl halides in high yields. Furthermore, the aryl thiols are used in situ for the synthesis of more advanced molecules such as diaryl sulfides and benzothiophenes.

Reductive removal of methoxyacetyl protective group using sodium borohydride

Herein, we have developed a mild and selective reductive deprotection method for the MAc protected alcohols using sodium borohydride. The new deprotection conditions provide a complete orthogonality between O-MAc and other protecting groups such as tert-butyl ester, N-Boc, Fmoc, Cbz, O-TBDMS, N-benzyl, O-benzyl, O-acetyl, N-acetyl, N-MAc, etc. In addition to O-MAc deprotection, this method is also applicable for S-MAc deprotection.

Thermal reactions of chloroarenes with hydrogen sulfide in the presence of methanol

Gas-phase reactions of chloroarenes (ClC6H4X, X = H, 4-CH3, 4-OH, 4-Cl, 4-CF3) with hydrogen sulfide or its precursors were investigated in the presence of methanol, which was a stronger H-donor than hydrogen sulfide. Introducing methanol increased the selectivity of arenethiols formation at X = H and 4-CH3 and did not affect the reaction selectivity at acceptor X. The efficiency of methanol influence was considered from the viewpoint of free-radical reaction mechanism and the stability of the arenethiyl radicals. 2005 Pleiades Publishing, Inc.

Chemoselective protection of thiols versus alcohols and phenols. The Tosvinyl group

The conjugate addition of aliphatic and aromatic thiols to ethynyl p-tolyl sulphone (tosylacetylene) has been managed to afford Tosvinyl derivatives chemoselectively (in the presence of oxygen nucleophiles) and stereoselectively (isomers Z) in practically quantitative yields. The conditions of choice are: catalytic amounts of Et3N (only 0.5-1.0 mol%), a reaction temperature around 0°C and, for the less acidic thiols, CF3CH2OH or CH3CN/CF3CH2OH as the solvent. Thus, N-Boc-Cys-OMe has been quantitatively protected as its S-Tosvinyl derivative in the presence of N-Boc-Ser-OMe and N-Boc-Tyr-OMe. This novel protecting group is stable to several basic and acidic conditions; its removal is achieved at rt by treatment with an excess of pyrrolidine or at 0°C with alkanethiolate ions.

Substrate mimetics-specific peptide ligases: studies on the synthetic utility of a zymogen and zymogen-like enzymes.

Although proteases are capable of synthesizing peptide bonds, they are not proficient at peptide fragment ligation. Further manipulations are needed to shift the native enzyme activity from the cleavage to the synthesis of peptides. This account reports on the synthetic potential of nonactivatable trypsinogen and zymogen-like enzymes designed to minimize proteolytic side reactions during peptide synthesis.

YELLOW COMPOUND AND WATER-BASED INK-JET RECORDING INK CONTAINING THE COMPOUND

Aqueous ink for ink-jet recording which contains at least a water-insoluble coloring matter, water and a resin as main components and which takes the form of an emulsion, in which is characterized by containing at least one yellow hue coloring matter selected from the group consisting of a quinophthalone compound represented by the formula (1); and a pyridone azo compound represented by the formula (2); The ink is ink for ink-jet recording having excellent light resistance and storage stability, and enables formation of a high quality image without blotting, and obtained recording image is excellent in water resistance as ink for ink-jet recording.

Aqueous ink for ink jet recording

Aqueous ink for ink jet recording which contains at least a water-insoluble coloring matter, water and a resin as main components and which takes the form of an emulsion, the coloring matter being represented by formula (1) The coloring matter for ink jet recording of the invention is excellent in water resistance in particular and also excellent in light resistance and compatibility with the resin. Thus, it is suited for ink jet recording. Further, the aqueous ink for ink jet recording of the invention which is produced using the coloring matter is excellent in light resistance and storage stability. Especially, when it is used as ink for ink jet recording system, the use of the ink composition can provide excellent aqueous ink that enables formation of a high-quality image without blotting and a recorded image having an excellent water resistance.