23982-57-2

Usage

Uses

Used in Organic Synthesis:
(Benzylmethylamino)acetone is used as a building block in the production of various pharmaceuticals and other organic compounds, contributing to the diversity and complexity of synthesized molecules.
Used in Manufacturing Protective Coatings, Adhesives, and Plastics:
(Benzylmethylamino)acetone serves as a key component in the formulation of protective coatings, adhesives, and plastics, enhancing their performance and durability.
Used in Pharmaceutical Development:
BMAA is used as a scaffold for the development of new drugs and therapeutic agents, leveraging its structural properties to create novel pharmaceutical compounds.
Used in Research and Development:
(Benzylmethylamino)acetone is utilized in research and development for its biological activity, with ongoing studies exploring its potential neurotoxic effects and implications in neurodegenerative diseases.

Upstream product

• 103-67-3 benzyl-methyl-amine 
• 598-31-2 1-bromoacetone 
• 62004-76-6 ethyl N-methyl-N-(phenylmethyl)glycine 
• 16812-43-4 bis(trimethylstannyl)methane 
• 105104-40-3 Okahara's reagent 
• 113258-86-9 1-(2-iodophenyl)-N-methylmethanamine 
• 622-29-7 N-Benzylidenemethylamine 
• 1634-04-4 tert-butyl methyl ether 
• 78-95-5 chloroacetone 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 140420-19-5 1-[(2-Iodo-benzyl)-methyl-amino]-propan-2-one 

Downstream Products

• 199187-88-7 N-Methylbenzylamino-acetonaethylenketal 
• 945257-35-2 C₁₅H₂₃O₃N 
• 1084889-68-8 C₁₅H₂₅NO₂ 
• 532410-39-2 1-(tert-butoxycarbonyl(methyl)amino)propan-2-one 
• 91339-81-0 1-(N-benzyl-N-methylamino)-2-propyl alcohol 
• 95961-96-9 1-(benzyl-methyl-amino)-2-[1-(2-diethylamino-ethyl)-indol-2-yl]-propan-2-ol 
• 69079-21-6 Benzyl-methyl-(2-triethylsilanyloxy-allyl)-amine 
• 73193-38-1 Benzyl-methyl-((E)-2-triethylsilanyloxy-propenyl)-amine 

Relevant academic research and scientific papers

PREPARATION METHOD FOR DEUTERATED MACROCYCLIC COMPOUND

Provided are a compound as represented by formula (D) and a preparation method therefor, where X2 is a halogen, Pg is selected from H and an amino protecting group, such as Cbz, Boc, Fmoc, Alloc, Teoc, methoxycarbonyl or ethoxycarbonyl. Also pr

Electrochemical, Iodine-Mediated α-CH Amination of Ketones by Umpolung of Silyl Enol Ethers

The electrochemical, oxidative Umpolung reaction of silyl enol ethers utilizing simple iodide salts for the synthesis of α-amino ketones is described. The products were isolated in excellent yields of up to 100percent, and various functionalized starting materials were accepted in an undivided electrochemical cell design. Moreover, a sensitivity assessment to ensure an improved reproducibility of the reaction and cyclic voltammetry experiments were performed to postulate a plausible reaction mechanism on their basis.

SOLID FORMS OF A MACROCYCLIC KINASE INHIBITOR

This invention relates to crystalline solvates of (10R)-7-amino-12-fluoro-2,10,16- trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benz- oxadiazacyclotetradecine-3-carbonitrile, useful in the treatment of abnormal cell growt

Novel, Acyclically Substituted Furopyrimidine Derivatives and Use Thereof

The present application relates to novel, acyclically substituted furopyrimidine derivatives, methods for their production, their use for the treatment and/or prophylaxis of diseases and their use for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.

Total Synthesis of 2,6-Dimethylergolin-8α-amines

A stereoselective total synthesis of the racemic form of the 2,6-dimethylergolin-8α-amine derivative III, previously obtained semi-synthetically from lysergic acid, is described. Starting from the commercially available tricyclic lactam 1, the 9,10-didehy

A convenient synthesis of 4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols by a novel intramolecular Barbier reaction and by an insertion reaction: Reaction scope and limitations

4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from N-(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.

Trisubstituted (Stannylmethyl)lithium as a Methylene Double Anion Equivalent. Reaction with Esters

Trisubstituted (stannylmethyl)lithium reacts with electrophiles as a methylene double anion equivalent to produce enolates from esters.The reaction mechanism is discussed.

2-(Chloromethyl)-3,5-dioxahex-1-ene. An Effective Acetonylating Reagent

By β-elimination of 2-chloro-1-(chloromethyl)ethyl methoxymethyl ether (1) under solid-liquid phase-transfer catalytic conditions, 2-(chloromethyl)-3,5-dioxahex-1-ene (2) of high purity was readily obtained in 85percent.Allyl chloride (2) is found to be stable at ambient conditions and to be a superior reagent as CH3COCH2+ synthon for converting active proton-containing compounds such as carboxylic acids, amines, phenols, alcohols, thiols, malonate, β-diketones, β-keto esters, phenylacetonitrile, fluorene, and indene to the corresponding acetonyl derivatives in good to excellent yields (61-93percent), usually under phase-transfer catalytic conditions or in a t-BuONa-t-BuOH system.

Synthesis and Properties of Cyclic Keto Alkenylammonium Salts

The cyclic keto alkenylammonium salts (4)-(8) have been prepared by a short, general route and their acidic and electrophilic properties examined.

Specific Enolates from α-Amino Ketones

The enolization of 11 tertiary α-amino ketones was investigated under three different conditions (kinetic base, thermodynamic base, thermodynamic acid) to determine the directionality of such enolates for application to alkaloid synthesis.The ketone structural variables examined were the geometry of the amine nitrogen lone pair-carbonyl array and the electronic nature of the nitrogen substituent.With the exception of 3-pyrrolidinones, increasing the electron-withdrawing nature of the nitrogen increases the amount of enolization toward nitrogen (3, 6, and 9 or 21, 24, and 27).N-Alkyl-substituted amino ketones (3, 12, 21, 33) under kinetic base conditions yield enolate distributions similar to those of the corresponding all-carbon compounds.N-Carbamato-substituted amino ketones (6, 24, 27, 30) enolize predominantly toward nitrogen under all conditions.The 3-pyrrolidinones 12, 15, and 18 afford enolates away from nitrogen under all conditions.