23997-80-0

Upstream product

• 829-20-9 2',4'-dimethoxyacetophenone 
• 151-10-0 1,3-Dimethoxybenzene 

Downstream Products

• 99075-67-9 thioacetic acid-(2,4-dimethoxy-anilide) 
• 71516-64-8 1-(2,4-Dimethoxy-phenyl)-ethanone O-[1-(2,4-dimethoxy-phenyl)-eth-(E)-ylideneaminooxymethyl]-oxime 
• 5078-07-9 6-hydroxy-2-methylbenzoxazole 
• 23999-64-6 6-methoxy-2-methyl-benzoxazole 
• 829-20-9 2',4'-dimethoxyacetophenone 
• 188894-33-9 α-(2,4-dimethoxyphenyl)ethyl amine 

Relevant academic research and scientific papers

Preparation method of S-configuration phenyl ethyl amine hydrochloride compound

The invention relates to a preparation method of an S-configuration phenyl ethyl amine hydrochloride compound, and relates to the technical field of medicine synthesis and preparation. The preparationmethod comprises the following steps: (1) carrying out Friedel-Crafts reaction on m-dimethoxy benzene and acetyl chloride under the condition of Lewis acid to generate an intermediate A; (2) reactingthe intermediate A with hydroxylamine hydrochloride without separation to generate an intermediate B; (3) reducing the intermediate B under the condition of a reducing agent to obtain a compound C; (4) carrying out organic acid resolution on the compound C to obtain an S-configuration compound D organic salt; and (5) dissociating and salifying the organic salt to obtain a target product compoundE. The preparation method disclosed by the invention has the characteristics of simple purification, low cost, high efficiency, high yield and suitability for industrial mass production.

Rhodium(III)-Catalyzed Direct C-H Arylation of Various Acyclic Enamides with Arylsilanes

The stereoselective β-C(sp2)-H arylation of various acyclic enamides with arylsilanes via Rh(III)-catalyzed cross-coupling reaction was illustrated. The methodology was characterized by extraordinary efficacy and stereoselectivity, a wide scope of substrates, good functional group tolerance, and the adoption of environmentally friendly arylsilanes. The utility of this present method was evidenced by the gram-scale synthesis and further elaboration of the product. In addition, Rh(III)-catalyzed C-H activation is considered to be the critical step in the reaction mechanism.

Preparation method of pyrimidine salicylate oxime ester compound and application of compound as herbicide

The invention discloses a preparation method of a pyrimidine salicylate oxime ester compound and application of the compound as a herbicide, belongs to the technical field of herbicides, and relates to the application of the herbicide in selectively controlling gramineous weeds and broadleaf weeds for crops. The compound is a pyrithiobac oxime ester compound. The preparation method includes the following steps that acids of pyrithiobac are condensed with substituted acetophenoxime in the presence of an organic solvent and a condensation agent to prepare a (I) compound. At 45 g a.i./hm, thecompound can effectively control echinochloa crusgalli, eleusineindica, setaria viridis, amaranthus retroflexus, portulaca oleracea, chenopodium album and other grassy weeds and broadleaf weeds, can serve as a candidate herbicide in a cotton field and has potential industrial application. Meanwhile, the compound is environmentally friendly, low in toxicity and highly safe for crops such as cotton.The invention provides a preparation technology of the efficient and safe novel pyrimidine salicylate oxime ester compound with the herbicidal activity, the compound can be massively produced, the yield is high and the purity is high.