2401-47-0

Basic information

• Product Name: 2-(4-chlorophenoxy)-N,N-dimethylethanamine
• Synonyms: 2-(4-chlorophenoxy)-N,N-dimethylethanamine;2-(4-Chlorophenoxy)-N,N-dimethylethylamine;N,N-Dimethyl-2-(4-chlorophenoxy)ethanamine
• CAS NO: 2401-47-0
• Molecular Formula: C₁₀H₁₄ClNO
• Molecular Weight: 200
• Mol File: 2401-47-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 267℃
• Flash Point: 115℃
• Appearance: /
• Density: 1.096
• Storage Temp.: 2-8°C
• PKA: 8.59±0.28(Predicted)
• CAS DataBase Reference: 2-(4-chlorophenoxy)-N,N-dimethylethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenoxy)-N,N-dimethylethanamine(2401-47-0)
• EPA Substance Registry System: 2-(4-chlorophenoxy)-N,N-dimethylethanamine(2401-47-0)

Safety Data

• Hazardous Substances Data: 2401-47-0(Hazardous Substances Data)

Usage

Description

2-(4-chlorophenoxy)-N,N-dimethylethanamine, also known as dimethylaminoethyl 4-chlorophenoxyacetate, is an organic compound belonging to the phenylpropanoid class. It has the chemical formula C10H14ClNO2 and appears as a clear liquid.

Uses

Used in Agricultural Industry:
2-(4-chlorophenoxy)-N,N-dimethylethanamine is used as a herbicide and plant growth regulator for controlling the growth of unwanted plants. It functions by disrupting auxin transport, leading to uncontrolled growth and ultimately causing the death of the targeted plants.
However, its use is regulated in some regions due to potential environmental and health risks, such as the risk of groundwater contamination.

Upstream product

• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 106-48-9 4-chloro-phenol 
• 105-58-8 Diethyl carbonate 
• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 

Downstream Products

• 2764-21-8 C₃₀H₄₈Cl₂N₂O₂⁽²⁺⁾*2Br^(1-) 
• 98345-97-2 (4-Bromo-benzyl)-[2-(4-chloro-phenoxy)-ethyl]-dimethyl-ammonium; bromide 
• 98654-55-8 (2-Chloro-benzyl)-[2-(4-chloro-phenoxy)-ethyl]-dimethyl-ammonium; chloride 
• 98654-57-0 <4-Chlor-benzyl>-<2-(4-chlor-phenoxy)-aethyl>-dimethyl-ammoniumchlorid 
• 98345-80-3 [2-(4-Chloro-phenoxy)-ethyl]-dimethyl-(4-nitro-benzyl)-ammonium; chloride 

Relevant articles and documents

Mustard Carbonate Analogues as Sustainable Reagents for the Aminoalkylation of Phenols

N,N-dialkyl ethylamine moiety can be found in numerous scaffolds of macromolecules, catalysts, and especially pharmaceuticals. Common synthetic procedures for its incorporation in a substrate relies on the use of a nitrogen mustard gas or on multistep syntheses featuring chlorine hazardous/toxic chemistry. Reported herein is a one-pot synthetic approach for the easy introduction of aminoalkyl chain into different phenolic substrates through dialkyl carbonate (β-aminocarbonate) chemistry. This new direct alcohol substitution avoids the use of chlorine chemistry, and it is efficient on numerous pharmacophore scaffolds with good to quantitative yield. The cytotoxicity via MTT of the β-aminocarbonate, key intermediate of this synthetic approach, was also evaluated and compared with its alcohol precursor.