24010-56-8

Basic information

• Product Name: Benzenesulfonamide, 2,6-dimethyl- (9CI)
• Synonyms: Benzenesulfonamide, 2,6-dimethyl- (9CI)
• CAS NO: 24010-56-8
• Molecular Formula: C₈H₁₁NO₂S
• Molecular Weight: 185.24344
• Product Categories: SULFONAMIDE
• Mol File: 24010-56-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 112-113 °C
• Boiling Point: 344.3°C at 760 mmHg
• Flash Point: 162°C
• Appearance: /
• Density: 1.227g/cm³
• Vapor Pressure: 6.66E-05mmHg at 25°C
• Refractive Index: 1.554
• PKA: 10.27±0.60(Predicted)
• CAS DataBase Reference: Benzenesulfonamide, 2,6-dimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 2,6-dimethyl- (9CI)(24010-56-8)
• EPA Substance Registry System: Benzenesulfonamide, 2,6-dimethyl- (9CI)(24010-56-8)

Safety Data

• Hazardous Substances Data: 24010-56-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H11NO2S/c1-6-4-3-5-7(2)8(6)12(9,10)11/h3-5H,1-2H3,(H2,9,10,11)

Upstream product

• 7783-06-4 hydrogen sulfide 
• 87-62-7 2,6-dimethylaniline 
• 2905-29-5 2,6-dimethyl-benzene-sulfonyl chloride 

Downstream Products

• 13363-59-2 2,2'-dithiobis<3-methylbenzoic acid> 

Relevant articles and documents

Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase

Novel triazolopyrimidine acylsulfonamides class of antimycobacterial agents, which are mycobacterial acetohydroxyacid synthase (AHAS) inhibitors were designed by hybridization of known AHAS inhibitors such as sulfonyl urea and triazolopyrimidine sulfonamides. This Letter describes the synthesis and SAR studies of this class of molecules by variation of two parts of the molecule, the phenyl and triazolopyrimidine rings. SAR study describes optimisation of enzyme potency, whole cell potency and evidence of mechanism of action.