240122-01-4Relevant academic research and scientific papers
Sharpless asymmetric dihydroxylation of 5-aryl-2-vinylfurans: Application to the synthesis of the spiroketal moiety of papulacandin D
Balachari, Devan,O'Doherty, George A.
, p. 863 - 866 (2007/10/03)
Formula Presented Using the Sharpless catalytic asymmetric dihydroxylation reaction on 5-aryl-2-vinylfurans, diols are produced in high enantioexcess. The resulting diols can be efficiently transformed into the spiroketal ring precursor of the antifungal
Efficient synthesis of 5-aryl-2-vinylfurans by palladium catalyzed cross-coupling strategies
Balachari, Devan,Quinn, Liam,O'Doherty, George A.
, p. 4769 - 4773 (2007/10/03)
The synthesis of substituted 5-aryl-2-furfurals from furfural by three alternative palladium cross coupling strategies are described. The resulting 5-aryl-2-furfurals were converted into their corresponding 5-aryl-2- vinylfurans in good yields by Wittig chemistry.
