24014-19-5

Basic information

• Product Name: 4-METHYL-1H-PYRROLE-2-CARBALDEHYDE
• Synonyms: 4-METHYL-1H-PYRROLE-2-CARBALDEHYDE
• CAS NO: 24014-19-5
• Molecular Formula: C₆H₇NO
• Molecular Weight: 109.13
• Product Categories: Aldehydes;Pyrroles & Indoles;Pyrroles & Indoles
• Mol File: 24014-19-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 49-50 °C(Solv: hexane (110-54-3))
• Boiling Point: 226.065°C at 760 mmHg
• Flash Point: 95.796°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 0.084mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 15.50±0.50(Predicted)
• CAS DataBase Reference: 4-METHYL-1H-PYRROLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-1H-PYRROLE-2-CARBALDEHYDE(24014-19-5)
• EPA Substance Registry System: 4-METHYL-1H-PYRROLE-2-CARBALDEHYDE(24014-19-5)

Safety Data

• Hazardous Substances Data: 24014-19-5(Hazardous Substances Data)

Usage

General Description

4-Methyl-1H-pyrrole-2-carbaldehyde, also known as 4-methyl-2-formyl-1H-pyrrole, is a chemical compound with the molecular formula C6H7NO. It is a yellow to brownish liquid with a strong, sweet odor. 4-METHYL-1H-PYRROLE-2-CARBALDEHYDE is mainly used as a flavoring agent in the food and beverage industry, particularly in the production of coffee and cocoa flavors. It is also utilized in the manufacture of pharmaceuticals and in organic synthesis. Additionally, 4-methyl-1H-pyrrole-2-carbaldehyde is known to exhibit antimicrobial and antifungal properties, making it valuable for use in disinfectants and antimicrobial agents. However, it is important to handle this compound with care, as it can be hazardous if not properly managed.

InChI:InChI=1/C6H7NO/c1-5-2-6(4-8)7-3-5/h2-4,7H,1H3

Upstream product

• 616-43-3 3-methylpyrrole 
• 74-90-8 hydrogen cyanide 
• 123-54-6 acetylacetone 
• 94781-44-9 5-Formyl-3-methyl-1H-pyrrol-2-carbonsaeure-benzylester 
• 40236-19-9 benzyl 3,5-dimethylpyrrole-2-carboxylate 
• 2199-44-2 3,5-dimethyl-2-ethoxycarbonyl-1H-pyrrole 
• 134209-74-8 5-Formyl-3-methyl-1H-pyrrol-2-carbonsaeure 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 179928-11-1 6-methyl-3-[(4-methylphenyl)sulfonyl]pyrrolo[1,2-c]pyrimidine 
• 187842-18-8 1-Benzenesulfonyl-4-methyl-1H-pyrrole-2-carbaldehyde 

Relevant articles and documents

PYRROLOTRIAZINONES AND IMIDAZOTRIAZINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS

The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.

Pyrrolotriazine inhibitors of kinases

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

LITHIATION OF THE DIMER OF 3-BROMO-6-DIMETHYLAMINO-1-AZAFULVENE. EFFICACIOUS SYNTHESIS OF 4-MONO- AND 4,5-DISUBSTITUTED PYRROLE-2-CARBOXALDEHYDES.

The dimer 1a of 3-bromo-6-dimethylamino-1-azafulvene, is shown to function as a formal equivalent of 4-lithio- or 4,5-dilithiopyrrole-2-carboxaldehyde and consequently it is a progenitor, par excellence, of 4-mono- and 4,5-disubstituted pyrrole-2-carboxaldehydes.