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3-Nitropyridine 1-oxide is a chemical compound with the molecular formula C5H4N2O3. It is a derivative of pyridine, a heterocyclic aromatic compound, where one of the hydrogen atoms is replaced by a nitro group (-NO2) and the molecule is further oxidized to form a 1-oxide. 3-NITROPYRIDINE1-OXIDE is characterized by its yellow crystalline appearance and is soluble in organic solvents. It is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. Due to its reactivity, 3-nitropyridine 1-oxide should be handled with care, and appropriate safety measures should be taken during its storage and use.

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  • 2403-01-2 Structure
  • Basic information

    1. Product Name: 3-NITROPYRIDINE1-OXIDE
    2. Synonyms: 3-NITROPYRIDINE1-OXIDE
    3. CAS NO:2403-01-2
    4. Molecular Formula: C5H4N2O3
    5. Molecular Weight: 140.09686
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2403-01-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 397.2°Cat760mmHg
    3. Flash Point: 194°C
    4. Appearance: /
    5. Density: 1.43g/cm3
    6. Vapor Pressure: 3.7E-06mmHg at 25°C
    7. Refractive Index: 1.601
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-NITROPYRIDINE1-OXIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-NITROPYRIDINE1-OXIDE(2403-01-2)
    12. EPA Substance Registry System: 3-NITROPYRIDINE1-OXIDE(2403-01-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2403-01-2(Hazardous Substances Data)

2403-01-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2403-01-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,0 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2403-01:
(6*2)+(5*4)+(4*0)+(3*3)+(2*0)+(1*1)=42
42 % 10 = 2
So 2403-01-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H4N2O3/c8-6-3-1-2-5(4-6)7(9)10/h1-4H

2403-01-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-nitro-1-oxidopyridin-1-ium

1.2 Other means of identification

Product number -
Other names 3-nitropyridine N-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2403-01-2 SDS

2403-01-2Relevant articles and documents

Regioselective Three-Component Reaction of Pyridine N-Oxides, Acyl Chlorides, and Cyclic Ethers

Jones, D. Heulyn,Kay, Steven T.,McLellan, Jayde A.,Kennedy, Alan R.,Tomkinson, Nicholas C. O.

supporting information, p. 3512 - 3515 (2017/07/17)

A novel three-component reaction of pyridine N-oxides, acyl chlorides, and cyclic ethers is described. Treatment of an electron-deficient pyridine N-oxide with an acyl chloride in the presence of a cyclic ether at 25-50 °C leads to a substituted pyridine as a single regioisomer in up to 58% isolated yield. Isotopic-labeling experiments and substrate scope support the reaction proceeding through a carbene intermediate.

2-Aminopyridines via reaction of pyridine N-oxides and activated isocyanides

Vamos, Mitchell,Cosford, Nicholas D. P.

, p. 2274 - 2280 (2014/04/03)

A practical and efficient method for the synthesis of substituted 2-aminopyridines from pyridine N-oxides is reported. Yields of purified, isolated products of up to 84% are observed for the one-pot, two-step process. The reaction involves an in situ depr

OXIDATIVE DEMETHYLATION OF SOME METHYLNITROPYRIDINE 1-OXIDES

Achremowicz, Lucjan

, p. 2433 - 2434 (2007/10/02)

3-Nitropyridine 1-oxide and 5-methyl-3-nitropyridine 1-oxide are produced readily by oxidative demethylation using SeO2 of 2-methyl- and 2,5-dimethyl-3-nitropyridine 1-oxides.

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