2530-26-9 Usage
Uses
3-Nitropyridine is used in the novel synthesis of biologically active nitro heterocyclic compounds.
Synthesis
In 1993 Suzuki and co-workers reported the nitration of pyridine with nitrogen dioxide and ozone in dichloromethane at room temperature. They obtained a 3.5 % yield of 3-nitropyridine and 1.2 % of 3,5-dinitropyridine. 3-Nitropyridines can also be synthesized by oxidation of 3-aminopyridine with hydrogen peroxide in fuming sulphuric acid in 45% yield. Nitration of 2,6-dichloropyridine with nitronium tetrafluoroborate gave a 11% yield of 3-nitropyridine after dehalogenation. 3-nitropyridine has also been prepared from 2- chloro-3-nitropyridine.
Check Digit Verification of cas no
The CAS Registry Mumber 2530-26-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,3 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2530-26:
(6*2)+(5*5)+(4*3)+(3*0)+(2*2)+(1*6)=59
59 % 10 = 9
So 2530-26-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H4N2O2/c8-7(9)5-2-1-3-6-4-5/h1-4H
2530-26-9Relevant articles and documents
Exploration of relative chemoselectivity in the hydrodechlorination of 2-chloropyridines
Kinarivala, Nihar,Trippier, Paul C.
supporting information, p. 5386 - 5389 (2015/01/16)
The chemoselectivity of hydrodechlorination in 2-chloropyridine derivatives possessing reduction-sensitive functionalities is examined. The reaction conditions employed tolerate a variety of functionalities illustrating highly chemoselective hydrodechlorination in the presence of nitrile, allyl, terminal olefin, and nitroamine functionalities in excellent yield. Chemoselective deprotection of carboxybenzyl ethers is illustrated in moderate yield.
Reductive cleavage of heteroaryl C-halogen bonds by iodotrimethylsilane. Facile and regioselective dechlorination of antibiotic pyrrolnitrin
Sako,Kihara,Okada,Ohtani,Kawamoto
, p. 3610 - 3612 (2007/10/03)
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