24030-11-3Relevant academic research and scientific papers
TCT (2,4,6-trichloro-1,3,5-triazine) promoted single-step synthesis of 4,6-diarylpyrimidin-2(1H)-ones under microwave irradiation
Khosropour, Ahmad R.,Mohammadpoor-Baltork, Iraj,Khodaei, Mohammad M.,Jokar, Mabubeh
, p. 1551 - 1557 (2006)
An efficient single-step procedure for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones promoted by Zn(OTf)2-TCT or Bi(OTf)3-TCT under solvent-free microwave irradiation conditions has been developed.{A figure is presented}.
4,6-Diaryl/heteroarylpyrimidin-2(1H)-ones as a new class of xanthine oxidase inhibitors
Shukla, Shiwani,Kumar, Dinesh,Ojha, Ritu,Gupta, Manish K.,Nepali, Kunal,Bedi, Preet M. S.
, p. 486 - 495 (2014/07/21)
Summary A series of 4,6-diaryl/heteroarylpyrimidones was synthesized employing silica-supported fluoroboric acid under solvent-free conditions in a microwave reactor. The catalytic influence of HBF4-SiO2 was investigated in detail to
Biginelli-like cyclocondensation reaction: Efficient synthesis of 4,6-diarylpyrimidin-2(1H)-one under solvent-free conditions
Dai, Yisi,Cao, Minxiang,Zhuang, Mengjie,Xia, Sheng,Tu, Shujiang,Rong, Liangce
experimental part, p. 3039 - 3044 (2011/09/12)
An efficient and facile synthesis of 4,6-diarylpyrimidin-2(1H)-one via a Biginelli-like reaction of aromatic aldehydes, aromatic ketones, and urea in the presence of NaOH under solvent-free conditions using a heating method has been developed. Compared wi
Pyrimidinones as Casein Kinase II (CK2) Modulators
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Page/Page column 30, (2009/09/07)
A compound having Formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1 and R2 are defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.
