24049-46-5Relevant academic research and scientific papers
Preparation of functionalized aryl- and heteroarylpyridazines by nickel-catalyzed electrochemical cross-coupling reactions
Sengmany, Stephane,Leonel, Eric,Polissaint, Frantz,Nedelec, Jean-Yves,Pipelier, Muriel,Thobie-Gautier, Christine,Dubreuil, Didier
, p. 5631 - 5636 (2007)
(Chemical Equation Presented) A general efficient electrochemical method for the preparation of aryl- and heteroarylpyridazines in a nickel-catalyzed cross-coupling reaction of 3-chloro-6-methoxypyridazine and 3-chloro-6- methylpyridazine with a range of functionalized aryl or heteroaryl halides is reported.
Synthesis of substituted 3-amino-6-arylpyridazines via Suzuki reaction
Parrot,Rival,Wermuth
, p. 1163 - 1168 (2007/10/03)
Starting from the commercially available 3,6-dichloropyridazine, N3- substituted 3-amino-6-arylpyridazines were prepared in good yields and under mild conditions by means of two simple steps: a nucleophilic substitution and a palladium-catalyzed Suzuki coupling.
