240800-48-0 Usage
Uses
Used in Pharmaceutical Industry:
2,3,5-Trifluorobenzoyl chloride is used as a reagent for the synthesis of various pharmaceuticals. Its unique properties contribute to the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3,5-Trifluorobenzoyl chloride is utilized as a reagent for the synthesis of agrochemicals, helping to create more effective and environmentally friendly pesticides and other agricultural products.
Used in Specialty Chemicals Production:
2,3,5-Trifluorobenzoyl chloride is employed as a reagent in the synthesis of specialty chemicals, which are used in a wide range of applications, including coatings, adhesives, and advanced materials.
Used in Polymer Industry:
2,3,5-TRIFLUOROBENZOYL CHLORIDE is used in the production of polymers, where its properties can enhance the performance characteristics of the resulting polymers, such as their thermal stability, mechanical strength, and chemical resistance.
Used in Dye Industry:
2,3,5-Trifluorobenzoyl chloride is utilized in the synthesis of dyes, contributing to the development of new dyes with improved colorfastness, brightness, and other desirable properties.
Used in Flavoring Industry:
In the flavoring industry, 2,3,5-Trifluorobenzoyl chloride is used in the production of flavorings, where its unique chemical structure can contribute to the creation of novel and appealing taste profiles for food and beverage products.
Check Digit Verification of cas no
The CAS Registry Mumber 240800-48-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,0,8,0 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 240800-48:
(8*2)+(7*4)+(6*0)+(5*8)+(4*0)+(3*0)+(2*4)+(1*8)=100
100 % 10 = 0
So 240800-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H2ClF3O/c8-7(12)4-1-3(9)2-5(10)6(4)11/h1-2H
240800-48-0Relevant academic research and scientific papers
Novel quinazoline derivatives bearing various 6-benzamide moieties as highly selective and potent EGFR inhibitors
Hou, Weijie,Ren, Yan,Zhang, Zhenhua,Sun, Huan,Ma, Yongfen,Yan, Bo
, p. 1740 - 1750 (2018/03/12)
A series of novel quinazoline derivatives bearing various C-6 benzamide substituents were synthesized and evaluated as EGFR inhibitors, and most showed significant inhibitory potency against EGFR kinase. In particular, compound 6g possessed potent inhibitory activity against EGFR wild-type (IC50 = 5 nM), and strong antiproliferative activity against HCC827 and Ba/F3 (L858R) cell lines. Kinase profiling against a panel of 365 kinases showed that 6g was highly selective for EGFR. Furthermore, 6g showed desirable properties in assays of liver microsome metabolic stability and cytochromes P450 inhibition and preliminary pharmacokinetic study. The overall attractive profile of 6g made it an interesting compound for further development.
MACROLONE COMPOUNDS
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Page/Page column 38, (2010/11/30)
A compound of formula (I) For use as antibacterial agents, compositions containing same, processes for their preparation and their use in therapy.
