24095-40-7

Usage

Uses

Due to the lack of specific information on the applications of 4-isocyanato-1-(trifluoroacetyl)piperidine, it is not possible to provide a detailed list of its uses in various industries. However, given the presence of the isocyanate and trifluoroacetyl groups, it can be inferred that 4-ISOCYANATO-1-(TRIFLUOROACETYL)PIPERIDINE may have potential applications in the chemical synthesis of various products, particularly in the fields of pharmaceuticals and materials science. Further research and experimentation would be required to determine its exact uses and benefits in these or other industries.

Upstream product

• 32752-54-8 4-(bromomethyl)benzophenone 
• 94341-52-3 (4-(azidomethyl)phenyl)(phenyl)methanone 

Relevant academic research and scientific papers

Catalytic Staudinger Reduction at Room Temperature

We report an efficient catalytic Staudinger reduction at room temperature that enables the preparation of a structurally diverse set of amines from azides in excellent yields. The reaction is based on the use of catalytic amounts of triphenylphosphine as a phosphine source and diphenyldisiloxane as a reducing agent. Our catalytic Staudinger reduction exhibits a high chemoselectivity, as exemplified by reduction of azides over other common functionalities, including nitriles, alkenes, alkynes, esters, and ketones.

Sustainable organophosphorus-catalysed Staudinger reduction

A highly efficient and sustainable catalytic Staudinger reduction for the conversion of organic azides to amines in excellent yields has been developed. The reaction displays excellent functional group tolerance to functionalities that are otherwise prone to reduction, such as sulfones, esters, amides, ketones, nitriles, alkenes, and benzyl ethers. The green nature of the reaction is exemplified by the use of PMHS, CPME, and a lack of column chromatography.