24108-44-9

Usage

Uses

Used in Plastics and Polymers Industry:
3,5,6-Triphenyl-1,2,4-triazine is used as a light stabilizer and UV absorber for enhancing the durability and resistance of plastics and polymers to degradation caused by exposure to sunlight. Its ability to absorb UV radiation helps protect materials from the damaging effects of sunlight, thereby extending their service life.
Used in Organic Synthesis:
3,5,6-Triphenyl-1,2,4-triazine serves as a building block in the synthesis of various organic materials. Its unique structure allows for the creation of functional molecules with specific properties, making it a valuable component in the development of new compounds for various applications.
Used in Pharmaceutical and Biological Research:
3,5,6-Triphenyl-1,2,4-triazine has been studied for its potential pharmaceutical and biological activities. It has shown promise as an anti-cancer agent, with researchers investigating its ability to target and inhibit the growth of cancer cells. Additionally, it has been explored as a fluorescence probe in biological imaging, where its optical properties can be utilized for visualizing and studying biological processes at the molecular level.

InChI:InChI=1/C21H15N3/c1-4-10-16(11-5-1)19-20(17-12-6-2-7-13-17)23-24-21(22-19)18-14-8-3-9-15-18/h1-15H

Upstream product

• 36289-76-6 benzil bis(benzoylhydrazone) 
• 55824-85-6 1,3-Diphenyl-1-benzoyloxy-3-oxo-2-aza-1-propen 
• 501-65-5 diphenyl acetylene 
• 28819-30-9 benzohydrazonamide 
• 134-81-6 benzil 
• 28819-30-9 benzamidrazone 
• 55-21-0 benzamide 
• 73720-51-1 3-Phenyl-6-pyridin-2-yl-[1,2,4,5]tetrazine 
• 618-39-3 benzamidin 
• 116178-05-3 3,6-diphenyl-1,2,4-triazine-5-carbonitrile 
• 133406-37-8 3,5,6-triphenyl-2,5-dihydro-1,2,4-triazin-4-ium chloride 
• 34177-11-2 3-chloro-5,6-diphenyl-1,2,4-triazine 
• 6830-78-0 3,6-diphenyl-1,2,4,5-tetrazine 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 484-47-9 lophine 
• 102469-79-4 3,5,6-triphenyl-1,2-dihydro-[1,2,4]triazine 
• 745-28-8 3,5,6-triphenyl-[1,2,4]triazine 1-oxide 
• 745-45-9 3,5,6-triphenyl-[1,2,4]triazine 2-oxide 
• 151724-24-2 1,3,4-Triphenyl-6,7-dihydro-5H-[2]pyrindine 
• 18076-30-7 3,4,5-triphenylpyrazole 
• 222720-56-1 4-acetylamino-3,4,5-triphenyl-4H-pyrazole 
• 222720-55-0 1,4-diacetyl-3,5,6-triphenyl-1,4-dihydro-1,2,4-triazine 
• 30081-56-2 1,3,4-triphenylisoquinoline 
• 58484-95-0 1-methyl-2-ohenyl-1H-phenanthro<9,10-d>imidazole 
• 120914-99-0 3-phenyl-phenanthro<9,10-e>-1,2,4-triazine 
• 33314-38-4 1-methyl-3,4,5-triphenyl-1H-pyrazole 
• 151724-51-5 Acetic acid 1,3,4-triphenyl-6,7-dihydro-5H-[2]pyrindin-5-yl ester 
• 151724-39-9 1,3,4-Triphenyl-6,7-dihydro-5H-[2]pyrindine 2-oxide 

Relevant academic research and scientific papers

Gold-Catalyzed Oxidation of Internal Alkynes into Benzils and its Application for One-Pot Synthesis of Five-, Six-, and Seven-Membered Azaheterocycles

Internal alkynes have been shown to undergo oxidation to substituted benzils (1,2-diarylethane-1,2-diones) by α-picoline N-oxide in the presence of Ph3PAuNТf2 (5 mol-%). In addition to the unsubstituted benzil, the method allows preparing, under markedly mild conditions (50 °C in chlorobenzene), various non-symmetrical products, including heteroaromatic versions thereof which are much more difficult to obtain otherwise. This gold(I)-catalyzed transformation was integrated into one-pot reaction sequence delivering a range of 5- to 7-membered ring systems (imidazoles, quinoxalines, 1,2,4-triazines, pyrazines, and 1,4-diazepines), thus linking these important heterocyclic motifs to the internal alkyne reagent space.

Synthesis of Azaphosphinines by Directed Inverse-Electron-Demand Hetero-Diels–Alder Reactions with Na(OCP)

Herein, a straightforward synthetic approach towards azaphosphinines is reported. The synthesis of 1,3- and 1,4-aza-λ3-phosphinines as well as 1,2,4-diaza-λ3-phosphinines by inverse-electron-demand hetero-Diels–Alder reactions of sod

Synthesis of 1,2,4-triazine derivatives via [4 + 2] domino annulation reactions in one pot

Simple and efficient [4 + 2] domino annulation reactions have been developed for the synthesis of 1,2,4-triazine derivatives. The strategies exhibit high performance with moderate to high yields, using easily available materials including ketones, aldehyd

Solvent-free synthesis of triazines using N-halosulfonamides

In this study, N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) were used as efficient catalysts for the one-pot synthesis of 3,5,6-trisubstituted-1,2,4-triazines from readily available acid hydrazides, ammo

Synthesis of trisubstituted 1,2,4-triazines in presence of NaHSO 4/SiO2

An efficient method for the synthesis of trisubstituted 1,2,4-triazines, phenanthro-1,2,4-triazines and acenaphtho-1,2,4-triazines derivatives by three-component condensation of benzil or phenanthrene-9,10-dione or acenaphthylene-1,2-dione, with acid hydr

Novel one pot synthesis of substituted 1,2,4-triazines

Substituted-1,2,4-triazines were conveniently prepared in one pot by the condensation of amides and 1,2-diketones in presence of base, followed by cyclisation with hydrazine hydrate.

One-pot synthesis of 1,2,4-triazines

1,2,4-Triazines have been prepared from the one-pot condensation reaction of acid hydrazide (1), ammonium acetate and dicarbonyl compounds (2) on the surface of silica gel in the presence of triethylamine under microwave irradiation.

PHOTOCHEMISTRY OF N-HETEROCYCLES, II PHOTOCHEMICALLY INDUCED REDUCTION AND OXIDATION OF SOME 2(4),5-DIHYDRO-1,2,4-TRIAZINES, HIGH PRESSURE LIQUID CHROMATOGRAPHY STUDIES

The salts 1a-1c, 2a, and 3a of the 3,5,6-triphenyl-2(4),5-dihydro-1,2,4-triazines 1-3 were irradiated with a high pressure mercury immersion lamp (λ300 nm) in various alcohols and the reactions were followed by HPLC.The singlet excited states of the cations of the salts 1a-1c, 2a and 3a are thought to act as single electron acceptors.The resulting radicals A are converted by proton transfer into the radical cations B, which may become stabilized either by recombination with a hydroxyalkyl radical and proton loss to give the adduct 10, or by successive reduction and ring contractions to yield the corresponding pyrazoles 4 and 5, or the imidazoles 6 and 7.The latter are smoothly photodehydrogenated to the corresponding phenanthro-imidazoles 8 and 9.The photoexcited cation of salt 1a is able to dehydrogenate the base 1 to the aromatic triazine 11.When irradiated in alcohol possessing α-hydrogen atoms, compound 11 is reduced and furnishes the ring contraction products 4 and 8.The relative amounts of the pyrazole 4 and of the phenanthroimidazole 8 depend on whether compound 1 or 11 is used as the starting material.This observation suggests two independent pathways for the formation of compound 8.A mechanistic interpretation of the total photochemical process is presented.

Uncondensed 1,2,4-Triazines: Part II - Mechanistic Pathway of Grignard Reaction on 1,2,4-Triazines

Phenylmagnesium bromide reacts with 3-chloro-5,6-diphenyl-1,2,4-triazine (I) to give eleven products (II-XI and an undefined product with m.p. 270 deg C).A suitable mechanism for their formation has been discussed.