116178-05-3Relevant articles and documents
One-step synthesis of 1,4-bis(het)arylisoquinolines by the reaction of 1,2,4-triazines with arynes
Kopchuk, Dmitry S.,Nikonov, Igor L.,Khasanov, Albert F.,Gundala, Sravya,Krinochkin, Alexey P.,Slepukhin, Pavel А.,Zyryanov, Grigory V.,Venkatapuram, Padmavathi,Chupakhin, Oleg N.,Charushin, Valery N.
, p. 978 - 984 (2019/11/16)
[Figure not available: see fulltext.] The reaction of 3,6-bis(het)aryl-1,2,4-triazines (hetaryl ≠ 2-pyridyl) with aryne intermediates generated in situ was studied. As a result, novel 1,4-bis(het)arylisoquinolines were synthesized with yields of up to 45%. The main rules of the reactions were studied, and the obtained experimental data were compared with those described in the literature.
STUDIES ON as-TRIAZINE DERIVATIVES. VIII. SYNTHESIS OF 5-SUBSTITUTED 1,2,4-TRIAZINES
Konno, Shoetsu,Ohba, Setsuya,Agata, Mitsuko,Aizawa, Yuichi,Sagi, Mataichi,Yamanaka, Hiroshi
, p. 3259 - 3264 (2007/10/02)
Dehydroxy-chlorination of 6-methyl-3-phenyl (3a), and 3,6-diphenyl-5-oxo-2,5-dihydro-1,2,4-triazine (3b) afforded the corresponding 5-chloro-1,2,4-triazines (4a,b).The chloro-1,2,4-triazines (4a,b) treated with sodium alkoxides or amines to give the 5-alk
