241127-72-0

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
Benzaldehyde, 2-bromo-3,6-dihydroxy(9CI) is used as an intermediate in the production of various chemicals for pharmaceutical and agrochemical synthesis. Its unique structure with bromine and hydroxyl groups allows for versatile chemical reactions, making it a valuable component in the synthesis of a wide range of compounds.
Used in Fragrance and Flavoring Industry:
Due to its sweet, almond-like aroma, Benzaldehyde, 2-bromo-3,6-dihydroxy(9CI) is used as a key ingredient in the fragrance and flavoring industry. Its pleasant scent and flavor profile make it suitable for use in a variety of products, including perfumes, colognes, and food products.
Used in Research and Industrial Applications:
Benzaldehyde, 2-bromo-3,6-dihydroxy(9CI) is widely used in research and industrial applications due to its versatility and unique properties. Its ability to participate in various chemical reactions and processes makes it a valuable tool for scientists and researchers in the development of new compounds and technologies.

Upstream product

• 1194-98-5 2,5-Dihydroxybenzaldehyde 
• 93-02-7 2,5-dimethoxybenzaldehyde 

Downstream Products

• 327163-78-0 2-bromo-6-hydroxy-3-methoxybenzaldehyde 
• 347840-56-6 [2-bromo-6-methoxy-3-(3-methyl-but-2-enyloxy)-benzyloxy]-tert-butyl-diphenyl-silane 
• 347840-55-5 2-bromo-3-(tert-butyl-diphenyl-silanyloxymethyl)-4-methoxy-6-(3-methyl-but-2-enyl)-phenol 
• 347840-57-7 2-bromo-3-(tert-butyl-diphenyl-silanyloxymethyl)-4,4-dimethoxy-6-(3-methyl-but-2-enyl)-cyclohexa-2,5-dienone 
• 347840-58-8 (2S,4S)-8-Bromo-7-(tert-butyl-diphenyl-silanyloxymethyl)-2,4-dimethyl-10-(3-methyl-but-2-enyl)-1,5-dioxa-spiro[5.5]undeca-7,10-dien-9-one 
• 1173179-02-6 C₁₆H₁₂O₄ 
• 1352277-19-0 C₁₂H₁₄BrNO₄ 
• 1352277-20-3 C₁₉H₃₂BrNO₅Si 
• 1352277-49-6 2-bromo-4-((tert-butyldimethylsilyl)oxy)-3-formylphenyl diethylcarbamate 

Relevant academic research and scientific papers

Asymmetric Total Syntheses and Structure Revisions of Eurotiumide A and Eurotiumide B, and Their Evaluation as Natural Fluorescent Probes

Asymmetric total syntheses and structure revisions of dihydroisocoumarin-type natural products, eurotiumide A and eurotiumide B have been described. The key features of these total syntheses are the asymmetric Shi epoxidation, regio- and stereoselective e

Total synthesis of (+)-clavilactone A and (-)-clavilactone B by ring-opening/ring-closing metathesis

The enantioselective total synthesis of natural enantiomers of clavilactones A and B has been achieved. A key feature of the synthesis is the use of a ring-opening/ring-closing metathesis, which allows the one-pot transformation of a strained cyclobutenecarboxylate into a γ-butenolide.

Synthesis, cytotoxicity and pro-apoptosis activity of isoquinoline quinones

Mansouramycins are newly isolated cytotoxic isoquinoline quinones from marine organism. To find novel anticancer agents, eighteen isoquinoline quinones 7a–7r as Mansouramycins analogs were designed and synthesized. Most of these compounds displayed modera

Concise syntheses of violaceoids A and C

The concise syntheses of two alkylated hydroquinone natural products, violaceoids A and C, were accomplished by a protecting-group-free method employing the commercially available 2,5-dihydroxybenzal-dehyde as the starting material. The key strategy of the syntheses is the utilization of alkenylboronic acid as both the coupling and temporary protective reagents to efficiently introduce the requisite alkenyl side chain of violaceoid A. Moreover, the synthesis of violaceoid C is reported here for the first time.

Total synthesis of the aglycone of IB-00208

Abstract A total synthesis of the aglycone of IB-00208 was accomplished in 22 steps using a newly developed approach towards polycyclic 1,4-dioxygenated xanthones from benzocyclobutenones. The generality of this entry to xanthones was initially established on several model systems before it was successfully applied to the construction of the hexacyclic core of the natural product. A new and potentially general approach towards angularly fused benzocyclobutenones using ring-closing metathesis (RCM) was also developed.

HCV PROTEASE INHIBITORS

The present invention discloses a compound of general formula (I); A is O, S, CH, NH or NR', when O links with Z3, Z1 is N or CRZ1, Z2 is CRZ2, when Z1 links with O, Z2 is CH, Z3 is C-Ar; Ra, Rb, Rc and Rd independently is H, OH, halogen or -Y1-Rm; A1 is NH or CH2; R1' is alkyl, aryl, cycloalkyl, heterocycloalkyl or heteroaryl; A2 is N, O or linking bond; R1 is hydrogen, or, R1 linking covalently with R3 forms C5-C9 saturated or unsaturated hydrocarbon chain substituted by O or N; R3 is alkyl, cycloalkyl, heterocycloalkyl, alkyl substituted by cycloalky etc; R4 is alkoxy-CO, alkyl-NHCO, (alkyl)2NCO, or formyl substituted by aryl, cycloalkyl, heterocycloalkyl.

HCV Protease Inhibitors

A compound of general formula (I); A is O, S, CH, NH or NR′, when O links with Z3, Z1 is N or CRZ1, Z2 is CRZ2, when Z1 links with O, Z2 is CH, Z3 is C—Ar; Ra, Rb, Rc and Rd independently is H, OH, halogen or —Y1—Rm; A1 is NH or CH2; R1′ is alkyl, aryl, cycloalkyl, heterocycloalkyl or heteroaryl; A2 is N, O or linking bond; R1 is hydrogen, or, R1 linking covalently with R3 forms C5-C9 saturated or unsaturated hydrocarbon chain substituted by O or N; R3 is alkyl, cycloalkyl, heterocycloalkyl, alkyl substituted by cycloalkyl etc; R4 is alkoxy-CO, alkyl-NHCO, (alkyl)2NCO, or formyl substituted by aryl, cycloalkyl, heterocycloalkyl.

Total syntheses of graphisin A and sydowinin B

Efficient syntheses of the highly substituted benzophenone graphisin A and the xanthone sydowinin B are described. Key steps involve aryl anion addition to substituted benzaldehyde derivatives, subsequent methyl ester installation, and dehydrative cycliza

Synthetic studies toward (+)-cortistatin A

We describe herein the synthesis of a late-stage intermediate en route to cortistatin A. Key transformations included a Snieckus-like cascade sequence culminating in a 6π-electrocyclization, an alkylative dearomatization, and the stereoselective functiona

Sporolide B: Synthetic studies

Studies directed toward the synthesis of the architecturally complex marine natural product sporolide B are described. Synthetic analysis suggested advanced hydroquinone and benzodiquinane fragments, which upon elaboration were successfully united via an