24113-61-9Relevant academic research and scientific papers
Rhodium-Catalyzed Carbonylative Synthesis of Aryl Salicylates from Unactivated Phenols
Ai, Han-Jun,Zhang, Youcan,Zhao, Fengqian,Wu, Xiao-Feng
, p. 6050 - 6054 (2020)
A rhodium-catalyzed carbonylative transformation of unactivated phenols to aryl salicylates is described. This protocol is characterized by utilizing 1,3-rhodium migration as the key step to provide direct access to synthesize ohydroxyaryl esters. Various desired aryl o-hydroxybenzoates were produced in moderate to excellent yields with bis(dicyclohexylphosphino)ethane (DCPE) as the ligand. Interestingly, diphenyl carbonate was formed as the main product when 1,3-bis(diphenylphosphino)propane (DPPP) was used as the ligand. A plausible reaction mechanism is proposed.
