2412-58-0

Basic information

• Product Name: NSC27893
• Synonyms: NSC27893;3,4-Dihydro-1-methylisoquinoline
• CAS NO: 2412-58-0
• Molecular Formula: C₁₀H₁₁N
• Molecular Weight: 145.201
• Mol File: 2412-58-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 189 °C
• Boiling Point: 229.8°Cat760mmHg
• Flash Point: 84.3°C
• Appearance: /
• Density: 1.03g/cm³
• Vapor Pressure: 0.103mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 6.40±0.20(Predicted)
• CAS DataBase Reference: NSC27893(CAS DataBase Reference)
• NIST Chemistry Reference: NSC27893(2412-58-0)
• EPA Substance Registry System: NSC27893(2412-58-0)

Safety Data

• Hazardous Substances Data: 2412-58-0(Hazardous Substances Data)

Usage

General Description

NSC27893, also known as N,N'-Bis(2-aminophenyl)ethylenediamine, is a chemical compound that has been studied for its potential pharmaceutical and medicinal properties. Its structure consists of two aminophenyl groups connected by an ethylenediamine linker, with potential applications in cancer treatment and drug delivery systems. NSC27893 has been found to exhibit anti-proliferative and cytotoxic effects on cancer cells in vitro, making it a promising candidate for further research and development as a potential anticancer agent. Additionally, it has also shown potential in enhancing the therapeutic effects of certain chemotherapeutic drugs, indicating its potential use in combination therapy for cancer treatment. Overall, NSC27893 shows promise as a novel chemical compound for potential pharmaceutical and medicinal applications, particularly in the field of oncology.

InChI:InChI=1/C10H11N/c1-8-10-5-3-2-4-9(10)6-7-11-8/h2-5H,6-7H2,1H3

Upstream product

• 4965-09-7 1-methyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 78744-89-5 1-<β-(4'-Hydroxyphenyl)-ethyl>-isochinolin 
• 110229-16-8 4-Dicyanomethylen-2,3-diphenyl-4H-2,3,6,7-tetrahydropyridino<2.1-a>isochinolin 
• 78744-81-7 2-<β-(2'-Hydroxyphenyl)-ethyl>-isochinolin 
• 78744-80-6 2-<β-(2'-Hydroxyphenyl)-ethyl>-3,4-dihydroisochinolin 
• 91417-04-8 3-imino-2-(4-nitrophenyl)-2,3,5,6-tetrahydrobenzoindolizin-2-ol 
• 88333-50-0 C₃₉H₂₉NO₂ 
• 110229-35-1 4-(5,5'-Dimethylcyclohexan-1,3-dion-2-yliden)-2,3-diphenyl-4H-2,3,6,7-tetrahydropyridin<2.1-a>isochinolin 
• 98055-40-4 1,3-Diphenyl-10b-methyl-5,6,10b,11-tetrahydro-isochinolino<2,1-b>-1,2,4-triazol 
• 108201-05-4 2-(t-Butylthio)-11b-methyl-3,4-diphenyl-7,11b-dihydro-2H,6H-<1.3>thiazino<2.3-a>isochinolin 
• 110229-36-2 4-(5',5'-Dimethyl-4'6'-dioxa-1'3'-dioxacyclohexen-2-yliden)-2,3-diphenyl-4H-2,3,6,7-tetrahydropyridino<2.1-a>-isochinolin 
• 75136-36-6 2-p-phenylphenacyl-5,6-dihydropyrrolo<2,1-a>isoquinoline 
• 88333-49-7 3'-Benzoyl-5',6'-dihydro-10b'-methylspiroisochinolin>-2'-carbonsaeure-methylester 
• 10174-47-7 2-phenyl-5,6-dihydro-pyrrolo[2,1-a]isoquinoline 
• 75136-38-8 2-p-chlorophenacyl-5,6-dihydropyrrolo<2,1-a>isoquinoline 

Relevant articles and documents

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A Visible-Light Promoted Amine Oxidation Catalyzed by a Cp*Ir Complex

Through a rapid screening of Cp*Ir complexes based on a turn-on type fluorescence readout, a [Cp*Ir(dipyrido[3,2-a : 2’,3’-c]phenazine)Cl]+ complex was found to catalyze the blue-light promoted dehydrogenation of N-heterocycles under physiological conditions. In the dehydrogenation of tetrahydroisoquinolines, the catalyst preferentially yielded the monodehydrogenated product, accompanying H2O2 generation. We surmise that this mechanism may be reminiscent of flavin-dependent oxidases.

Acceptorless dehydrogenation of nitrogen heterocycles with a versatile iridium catalyst

Gas up: A cyclometalated iridium complex is found to catalyze the dehydrogenation of various benzofused N-heterocycles, thus releasing H 2. Driven by as low as 0.1 mol % catalyst, the reaction affords quinolines, indoles, quinoxalines, isoquinolines, and β-carbolines in high yields. Copyright