24134-12-1

Basic information

• Product Name: 1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE
• Synonyms: 1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE;1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBOXALDEHYDE;2,3-DIMETHYL-3H-IMIDAZOLE-4-CARBALDEHYDE;1,2-Dimethyl-1H-imidazole-5-carboxaldehyde 97%;1,2-dimethyl-1H-imidazole-5-carbaldehyde(SALTDATA: FREE);2,3-dimethyl-4-imidazolecarboxaldehyde;2,3-dimethylimidazole-4-carbaldehyde
• CAS NO: 24134-12-1
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14
• Mol File: 24134-12-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 76 °C
• Boiling Point: 289°Cat760mmHg
• Flash Point: 128.6°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 0.00225mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.55±0.25(Predicted)
• CAS DataBase Reference: 1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE(24134-12-1)
• EPA Substance Registry System: 1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE(24134-12-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 24134-12-1(Hazardous Substances Data)

Usage

General Description

1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE is a chemical compound with the molecular formula C6H8N2O. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. 1,2-DIMETHYL-1H-IMIDAZOLE-5-CARBALDEHYDE is a colorless solid and is soluble in most organic solvents. It is also known for its use as a reagent in organic synthesis and as a building block in the production of various pharmaceutical compounds. Additionally, it has been studied for its potential biological and pharmacological properties, and has shown promise in certain applications such as antifungal and antitumor agents.

InChI:InChI=1/C6H8N2O/c1-5-7-3-6(4-9)8(5)2/h3-4H,1-2H3

Upstream product

• 24021-93-0 (1,2-dimethyl-1H-imidazol-5-yl)methanol 
• 1739-84-0 1,2-dimethyl-1H-imidazole 
• 80-48-8 methyl p-toluene sulfonate 
• 35034-22-1 2-methyl-1H-imidazole-4-carboxaldehyde 

Downstream Products

• 235092-26-9 (4-chloro-phenyl)-(2,3-dimethyl-3H-imidazol-4-yl)-methanol 
• 235092-28-1 (2,3-dimethyl-3H-imidazol-4-yl)-(4-methoxy-phenyl)-methanol 
• 235092-27-0 (2,3-dimethyl-3H-imidazol-4-yl)-p-tolyl-methanol 
• 1202524-75-1 ethyl 4-(acetyloxy)-1,2-dimethyl-1H-benzimidazole-6-carboxylate 
• 929533-65-3 4-hydroxy-1,2-dimethyl-1H-benzimidazole-6-carboxylic acid 
• 24021-93-0 (1,2-dimethyl-1H-imidazol-5-yl)methanol 
• 1599529-55-1 (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(1,2-dimethyl-1H-imidazol-5-yl)methanol 
• 235092-37-2 [5-(4-methoxy-benzoyl)-1-methyl-1H-imidazol-2-yl]-acetic acid ethyl ester 
• 235092-36-1 [1-methyl-5-(4-methyl-benzoyl)-1H-imidazol-2-yl]-acetic acid ethyl ester 
• 235092-34-9 [5-(4-chloro-benzoyl)-1-methyl-1H-imidazol-2-yl]-acetic acid ethyl ester 
• 235092-32-7 (2,3-dimethyl-3H-imidazol-4-yl)-(4-methoxy-phenyl)-methanone 

Relevant articles and documents

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE

The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): (wherein R6 and R7 may be the same or different and each represent a hydrogen atom or the like, R8, R9, R19, and R11 may be the same or different and each represent a hydrogen atom or the like, R1 represents lower alkyl which may be substituted with cycloalkyl, or the like, and R3 represents optionally substituted aryl or an optionally substituted heterocyclic group).

Novel farnesyl protein transferase inhibitors as antitumor agents

Disclosed are novel tricyclic compounds represented by the formula (1.0): and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.