24149-05-1

Basic information

• Product Name: 6,9,12-OCTADECATRIENOL
• Synonyms: 6,9,12-OCTADECATRIENOL;GAMMA-LINOLENYL ALCOHOL;DELTA 6-9-12 GAMMA LINOLENYL ALCOHOL;Y-linolenyl alcohol;γ-linolenyl alcohol
• CAS NO: 24149-05-1
• Molecular Formula: C₁₈H₃₂O
• Molecular Weight: 264.45
• Mol File: 24149-05-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 374.227°C at 760 mmHg
• Flash Point: 125.96°C
• Appearance: /liquid
• Density: 0.87g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.485
• Storage Temp.: −20°C
• PKA: 15.18±0.10(Predicted)
• CAS DataBase Reference: 6,9,12-OCTADECATRIENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 6,9,12-OCTADECATRIENOL(24149-05-1)
• EPA Substance Registry System: 6,9,12-OCTADECATRIENOL(24149-05-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 24149-05-1(Hazardous Substances Data)

Usage

Uses

γ-Linolenyl Alcohol is an inhibitor of African swine fever virus. An antiviral agent.

InChI:InChI=1/C18H32O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h6-7,9-10,12-13,19H,2-5,8,11,14-18H2,1H3/b7-6-,10-9-,13-12-

Upstream product

• 1243300-25-5 C₂₃H₃₈O₄ 
• 301-00-8 methyl linolenate 
• 506-26-3 all-cis-6,9,12-octadecatrienoic acid 

Downstream Products

• 25226-26-0 (6Z,9Z,12Z)-octadeca-6,9,12-trien-1-yl 4-methylbenzenesulfonate 
• 7324-41-6 cis-8,11,14-eicosatrienoic acid 
• 60187-52-2 γ-linolenyl mesylate 

Relevant articles and documents

PROCESS FOR PREPARING AND PURIFYING FATTY ACIDS

There is provided a process for purifying a fatty acid, which process comprises reacting a fatty acid with a lithium salt in a first solution and under conditions to allow formation of a precipitate of a lithium salt of the fatty acid; isolating the precipitate; dissolving the precipitate in a second solution followed by separation of the organic and aqueous layers so formed; and evaporating the organic layer to isolate the purified fatty acid. There is also provided a process for increasing the length of a fatty acid, and the use of a lithium salt to purify a fatty acid.

Optimization of synthetic conditions for the preparation of dihomo-γ-linolenic acid from γ-linolenic acid

Orthogonal experiments were employed to optimize the correlated parameters of reduction, sulfonation, substitution and hydrolysis. These reactions were used to convert γ-linolenic acids into dihomo-γ-linolenic acids (DGLA). For the reduction, the best rea

Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and Cdc25B inhibition

Selective inhibitors of protein tyrosine phosphatases (PTPs) and dual-specificity phosphatases (DSPs) are expected to be useful tools for clarifying the biological functions of the PTPs themselves and also to be candidates for novel therapeutics. We planned a library approach for the identification of PTP/DSP inhibitors in which 3-acyltetronic acid is used as a "core" phosphate mimic. A series of novel tetronic acid derivatives were synthesized and evaluated as inhibitors of the dual-specificity protein phosphatases VHR and cdc25B. Several compounds are found to be potent inhibitors of cdc25B, which is a key enzyme for cell-cycle progression. The promising results described herein strongly indicated that this tetronic acid library is potent as a library focused on the PTP/DSP-selective inhibitor.