24149-57-3Relevant articles and documents
1,2-Naphthoquinone-based Derivatives and and Methods for Preparing them
-
, (2016/11/24)
The present invention relates to a compound represented by chemical formula (1), a pharmaceutically acceptable salt, a hydrate, a solvate, a prodrug, a tautomer, an enantiomer, or a pharmaceutically acceptable diastereomer thereof, a preparing method thereof, and a medical composition having a treating or preventing effect of metabolic diseases containing the same. Here, R_1 to R_3, and X_1 to X_6 are the same as defined in a first claim.COPYRIGHT KIPO 2015
Synthesis of 1,5- and 1,8-diazaanthraquinones by reaction of aminoquinolinequinones with β-dielectrophiles
Marcos, Alicia,Pedregal, Carmen,Avendano, Carmen
, p. 1763 - 1774 (2007/10/02)
Easily obtained amino derivatives of quinoline-5,8-quinone (1 and 2) and 4-methyl-(1H)2,5,8-quinolinetrione (3) react with β-dielectrophiles, affording aminoalkylidenemalonates in a convenient procedure. These compounds cyclise thermally to 1,5-diaza-(1H)4,9,10-anthracenetriones (10 and 19), 1,8-diaza-(1H)4,9,10-anthracenetriones (11 and 20) and 1,5-diaza-(1H, 5H)2,8,9,10-anthracenetetraones (12 and 21). The strategy is less convenient when applied to aromatic precursors. Knorr cyclisation of β-oxoanilides fails in both systems.
