2416-19-5Relevant academic research and scientific papers
Bioactive tigliane diterpenoids from the latex of Euphorbia fischeriana
Deng, Yan-Yan,Qu, Bo,Zhan, Zhong-Lang,Wang, An-Qi,Zhou, Wei,Jia, Ming-Yue,Hua, Juan,Luo, Shi-Hong
supporting information, p. 179 - 187 (2021/01/12)
Latex is a type of sticky endogenous fluids derived from diverse plants including Euphorbia fischeriana, and is of great scientific and commercial values. In the current study, it was demonstrated that the latex extracted from E. fischeriana strongly respelled the growth of cotton bollworm, Helicoverpa armigera. Using spectroscopic methods, HPLC, and GC-MS analyses, six aliphatic tigliane diterpenoids were isolated from the latex of E. fischeriana, among which three compounds (2, 3, and 5) were new. Two major compounds (1 and 4) exhibited remarkable antifeedant activity against H. armigera, with EC50 values at 2.59 and 15.32 μg/cm2, respectively. In addition, the quantification analysis of diterpenoids in different organs indicated that 4 was the most abundant constituent and was highly accumulated in the latex. Collectively, the current study highlighted that the diterpenoids in latex of E. fischeriana had a considerable antifeedant function against H. armigera, which might be employed for the future development of natural insecticides for organic farming.
'Clean' hydrolase reactions using commercial washing powder
Zhang, Jie,Tonin, Fabio,Zhang, Wuyuan,Hagedoorn, Peter-Leon,Mallée, Lloyd,Hollmann, Frank
, p. 24039 - 24042 (2019/08/15)
We report the use of commercial laundry powder as a biocatalyst for a range of lipase-catalysed reactions including (trans)esterification, ester hydrolysis and chemoenzymatic epoxidation reactions. The enzymatic laundry powder exhibited excellent stability and recyclability, making it a readily available and cheap biocatalyst for chemical transformations.
NOVEL GLYCINE TRANSPORT INHIBITORS FOR THE TREATMENT OF PAIN
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Page/Page column 54; 55, (2018/08/12)
The present invention relates to novel glycine transport inhibitor compounds and their use for treating pain.
Preapration of 7,8,16-trihydroxy-hexadecanoic acid from aleuritic acid and a synthesis of E/Z-7-hexadecen-1,16-olides and hexalure
Tewari, Neera,Rohatgi, Amit,Bhushan, Kumar Hari,Subramanian, G. B. V.
, p. 851 - 855 (2007/10/03)
Both threo/erythro 7,8,16-trihydroxy-hexadecanoic acids have been preapred from threo/erythro 9,10,16-trihydroxy-hexadecanoic acids (aleuritic acid), by interchanging the positions of the terminal carboxyl and hydroxyl groups through steps of appropriate oxidation-reduction on the dithianes obtained from the 16-oxo-9,10-dihydroxy-hexadecanoic acids.Cyclization of the corresponding 9,10-olefin with dibutyl tin oxide furnish E/Z-7-hexadecen-1,16-olides.Preparation of the insect pheromone hexalure is also reported.
