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11α-hydroxypregna-1,4-diene-3,20-dione is a steroidal compound derived from the parent structure of pregnane, characterized by the presence of a hydroxyl group at the 11α position, a double bond between carbons 1 and 4, and ketone groups at carbons 3 and 20. This chemical is a member of the pregnane family, which is a class of steroid compounds that are precursors to various hormones, including corticosteroids and androgens. The specific functional groups and structural features of 11α-hydroxypregna-1,4-diene-3,20-dione contribute to its biological activity and potential applications in医药领域, such as in the synthesis of pharmaceuticals targeting hormonal imbalances or other conditions related to steroid metabolism.

2417-44-9

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2417-44-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2417-44-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,1 and 7 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2417-44:
(6*2)+(5*4)+(4*1)+(3*7)+(2*4)+(1*4)=69
69 % 10 = 9
So 2417-44-9 is a valid CAS Registry Number.

2417-44-9Downstream Products

2417-44-9Relevant academic research and scientific papers

Microbial hydroxylation of hydroxyprogesterones and α-glucosidase inhibition activity of their metabolites

Choudhary, Muhammad Iqbal,Nasir, Muhammad,Khan, Shamsun N.,Atif, Muhammad,Ali, Rahat A.,Khalil, Syed M.,Atta-ur-Rahman

, p. 593 - 599 (2007/10/03)

Microbial transformation of 11α-hydroxyprogesterone (1) with Cunninghamella elegans, Gibberella fujikuroi, Fusarium lini, and Candida albicans yielded 11α,15α,16α-trihydroxypregn-4-ene-3,20-dione (3), 11α-hydroxy-5α-pregnane-3,20-dione (4), 6β,11α- dihydroxypregn-4-ene-3,20-dione(5), 11α-hydroxypregna-1,4-diene-3,20-dione (6), 11α,17β-dihydroxyandrost-4-en-3-one (7), and 11α,15α-dihydroxypregn-4-ene-3,20-dione (8). On the other hand, microbial transformation of 17α-hydroxyprogesterone (2) with Cunninghamella elegans and Fusarium Uni yielded 11α,17α- dihydroxypregn-4-ene-3,20-dione (9), and 17α-hydroxypregna-1,4-diene-3,20- dione (10). The structures of the metabolites 3-10 were deduced on the basis of spectroscopic methods. Compound 3 was identified as a new metabolite, which exhibited a promising inhibitory activity against the α-glucosidase enzyme.

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