241819-85-2

Usage

Uses

Used in Pharmaceutical Industry:
Tert-Butyl 2-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate is used as a synthetic intermediate for the development of novel pharmaceutical compounds. Its unique structure and functional groups can be tailored to create new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical field, Tert-Butyl 2-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate serves as a key component in the synthesis of innovative agrochemicals. Its structural features and modifiable functional groups enable the creation of new pesticides or herbicides with improved efficacy and selectivity.
Used in Material Science:
Tert-Butyl 2-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate is utilized as a precursor in the development of advanced materials. Its unique molecular structure and functional groups can be exploited to design materials with specific properties, such as improved mechanical strength, thermal stability, or electrical conductivity.
It is crucial to handle and use Tert-Butyl 2-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate with care, as its properties and potential hazards may vary depending on the specific conditions and applications.

Upstream product

• 189149-23-3 tert-butyl 2-hydroxy-2,3-dihydrospiro[indene-1,4’-piperidine]-1‘-carboxylate 
• 137419-24-0 1'-(tert-butyloxycarbonyl)spiro<1H-indene-1,4'-piperidine> 
• 241819-84-1 N-tert-butoxycarbonyl-spiro<((2,3)-epoxy)indane-1,4'-piperidine> 
• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 
• 95-13-6 1-indene 
• 13292-87-0 dimethylsulfide borane complex 

Relevant academic research and scientific papers

Asymmetric synthesis of enantiomerically pure spiro [((2S)- hydroxy)indane-1,4'-piperidine]

We report herein, efficient and practical synthetic methods for the preparation of enantiomerically pure spiro[((2S)-hydroxy)indane-1,4'- piperidine] (S)-1, a key intermediate for the synthesis of a tachykinin receptor antagonist, using catalytic asymmetric reduction or catalytic asymmetric epoxidation as a key step.

Novel heterocyclic derivative capable of being used as SHP2 inhibitor

The invention relates to a novel heterocyclic derivative capable of being used as an SHP2 inhibitor, specifically relates to a compound shown by a formula I or pharmaceutically acceptable salts thereof, further relates to a use of the compound shown by the formula I or the pharmaceutically acceptable salts thereof and a pharmaceutical composition thereof in drug preparation, and particularly relates to a use in preparation of drugs for treatment, inhibition or prevention of diseases or discomforts mediated by SHP2 activity.

NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS

This invention relates to certain novel pyrazine derivatives (Formula I) as SHP2 inhibitors which is shown as formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention is directed to fused heterocyclic group derivatives useful as inhibitors of SHP2, methods for producing such compounds and methods for treating a SHP2-mediated disorder.