241823-97-2

Upstream product

• 144120-54-7 Nα-(9-fluorenylmethoxycarbonyl)-L-glutamic acid α-allyl ester 
• 241823-94-9 1-[Chloro-bis-(4-fluoro-phenyl)-methyl]-2,3,4,5,6-pentafluoro-benzene 
• 344-04-7 bromopentafluorobenzene 
• 345-92-6 4,4'-Difluorobenzophenone 
• 241823-93-8 2,3,4,4',4'',5,6-heptafluoro-triphenylmethanol 

Downstream Products

• 241824-04-4 (S)-2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-pentanedioic acid 1-allyl ester 5-[bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl] ester 
• 241823-99-4 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-[bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl] ester 

Relevant academic research and scientific papers

Modified Trityl Ester Protecting Groups in Peptide Synthesis

The novel, sterically demanding heptafluorotrityl- and phenylfluorenyl ester protecting groups were developed for the pro tection of the γ-carboxy group of glutamic acid. These trityl-type protecting groups exhibit a markedly increased stability compared to triphenylmethyl esters, and in addition the very mild cleavage conditions make their selective removal in the presence of other acid labile protecting groups such as tBu possible.