2419-74-1

Usage

Uses

Used in Chemical Synthesis:
1,4-Dichloro-2-butanol is used as a chemical intermediate for the production of other chemicals, playing a crucial role in the synthesis process due to its reactivity and functional groups.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1,4-Dichloro-2-butanol is used as a precursor in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Production:
1,4-Dichloro-2-butanol is also utilized in the agrochemical sector, serving as a starting material for the synthesis of pesticides and other agricultural chemicals, thereby supporting crop protection and yield enhancement.

InChI:InChI=1/C4H8Cl2O/c5-2-1-4(7)3-6/h4,7H,1-3H2

Upstream product

• 453-20-3 3-Hydroxytetrahydrofuran 
• 3068-00-6 D,L-1,2,4-butanetriol 
• 16714-78-6 1,4-dichloro-2-butanone 
• 78-93-3 butanone 

Downstream Products

• 59748-10-6 4-Chloro-1-(2-ethoxyphenoxy)-2-butanol 
• 59747-95-4 4-chloro-1-(4-chloro-3-methylphenoxy)-2-butanol 
• 59748-09-3 4-Chlor-1-(3-Chlor-Phenoxy)-2-butanol 
• 59748-00-4 4-chloro-1-(4-chlorophenoxy)-2-butanol 
• 59748-05-9 4-chloro-1-(4-methoxyphenoxy)-2-butanol 
• 116290-64-3 1-(4-bromophenoxy)-4-chloro-2-butanol 
• 116290-69-8 4-chloro-1-[4-(1,1-dimethylethyl)phenoxy]-2-butanol 
• 591-80-0 pent-4-enoic acid 
• 116290-70-1 4-(4-Chloro-2-hydroxy-butoxy)-benzamide 
• 116290-67-6 4-chloro-1-(3,4-dichlorophenoxy)-2-butanol 
• 116290-68-7 4-(4-Chloro-2-hydroxybutoxy)benzonitrile 
• 34680-20-1 α-[3-chloro-4-(3-hydroxypyrrolidino)-phenyl]-propionic acid 
• 775-15-5 1-benzyl-3-pyrrolidinol 
• 30727-14-1 N-ethyl-3-hydroxypyrrolidine 

Relevant academic research and scientific papers

Preparation method of N-substituent-3-hydroxytetrahydropyrrole

The invention discloses a preparation method of N-substituent-3-hydroxytetrahydropyrrole. The preparation method takes 1,2,4-butanetriol as a starting material, and comprises the following steps: performing a halogenating reaction between the starting material and hydrogen halide to prepare an intermediate 1,4-dihalogeno-2-butanol first, and then performing a condensation reaction with primary amine RNH2 to obtain a target product, wherein R represents methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tertiary butyl or benzyl; the halogenating reaction is performed in the presence of an acidic catalyst, and the acidic catalyst is formic acid or acetic acid; and hydrogen halide is hydrogen chloride or hydrogen bromide. The preparation method disclosed by the invention is relatively short in synthetic route, the starting material 1,2,4-butanetriol is low in price and easy to obtain, and other materials used in the method are relatively high in safety and also relatively low in price, so that the preparation method is suitable for industrial large-scale production. Particularly, the halogenating reaction can obtain a yield of 50% or above by selection of suitable halogenating agents and catalysts.

Aqueous-dispersible cyclic sulfonium compounds that cure to form water-insoluble polymers

Water-soluble sulfonium salts are converted, without the elimination of odorous volatile by-products, to water-insoluble products useful as binders in coating formulations by heating a water-soluble cyclic sulfonium salt in which the sulfonium sulfur is bonded only to aliphatic carbons.

Lithium or Bromomagnesium 1,4- and 1,5-Dilithioalkan-2-yloxides: Preparation and Synthetic Applications

Treatment of chloromethyl 2- or 3-chloroalkyl carbinols with butyllithium and then lithium naphthalenide or with ethylmagnesium bromide and then powdered lithium leads to the formation of lithium or bromomagnesium dilithiothioalkoxides, respectively, which represent trianionic species.The bromomagnesium 1,ω-dilithio-2-alkoxides undergo immediate elimination of lithium bromide and magnesium oxide to give ω-lithio-1-alkenes.These latter organometallic compounds as well as the lithium dithioalkoxides react with various electrophiles to afford functionalized compounds.

7-Substituted benzopyranes and process for the preparation thereof

The present invention relates to novel 7-substituted benzopyranes of formula (I), wherein R1 and R2 are hydrogen, alkyl of from 1 to 6 carbon atoms, hydroxyalkyl, alkenyl, cycloalkyl, phenylalkyl, dimethoxy-phenylalkyl, or R1 and R2 together with the joining nitrogen atom may represent a 5-7-membered heterocyclic ring, R3 is hydrogen, alkyl of from 1 to 4 carbon atoms or phenyl, R4 is hydrogen, R5 is hydrogen or phenyl, or R4 and R5 together may represent a bonding electron pair between the second and the third carbon atoms of the benzopyrane ring, R6 and R7 are hydrogen or they may represent an oxygen atom together, n is 1 or 2, with the proviso, that the pyrane ring may bear only one alkyl or phenyl substituent, and preparation process thereof. The novel compounds have valuable therapeutical effects, mainly in cardiotherapy.