42729-56-6

Usage

Uses

Used in Personal Care Products Industry:
1-Isopropyl-3-Pyrrolidinol is used as a solvent and surfactant for the production of personal care products, such as cosmetics and toiletries. Its properties contribute to the formulation's stability and effectiveness.
Used in Detergent and Cleaning Agents Industry:
1-Isopropyl-3-Pyrrolidinol is used as a stabilizer and emulsifier in the formulation of detergents and cleaning agents, enhancing their performance and ensuring a consistent texture.
Used in Cosmetics and Pharmaceuticals Industry:
1-Isopropyl-3-Pyrrolidinol is used as a stabilizer and emulsifier in the formulation of cosmetics and pharmaceuticals, ensuring the product's quality and shelf life.
Used in Disinfectant and Sanitizing Products Industry:
1-Isopropyl-3-Pyrrolidinol is used as an antimicrobial agent in disinfectant and sanitizing products, providing effective protection against harmful microorganisms.
Overall, 1-Isopropyl-3-Pyrrolidinol's versatility, safety, and environmental friendliness make it a preferred choice for use in a wide range of consumer products and industrial processes.

InChI:InChI=1/C7H15NO/c1-6(2)8-4-3-7(9)5-8/h6-7,9H,3-5H2,1-2H3

Upstream product

• 19398-47-1 1,4-dibromo-2-butanol 
• 2419-74-1 1,4-dichlorobutan-2-ol 
• 75-31-0 isopropylamine 
• 40499-83-0 pyrrolidin-3-ol 
• 67-64-1 acetone 

Downstream Products

• 1061749-46-9 C₂₄H₃₀N₆O₂ 
• 1430842-15-1 2-((2,4-dichlorobenzyl)oxy)benzaldehyde O-(1-isopropylpyrrolidin-3-yl) oxime 
• 1430842-14-0 2-((3-fluorobenzyl)oxy)benzaldehyde O-(1-isopropylpyrrolidin-3-yl) oxime 
• 1430842-13-9 2-((3,4-dichlorobenzyl)oxy)benzaldehyde O-(1-isopropylpyrrolidin-3-yl) oxime 
• 1430842-12-8 2-(benzyloxy)benzaldehyde O-(1-isopropylpyrrolidin-3-yl) oxime 
• 1430842-11-7 3-(trifluoromethyl)benzaldehyde O-(1-isopropylpyrrolidin-3-yl) oxime 
• 1430842-10-6 2-methoxybenzaldehyde O-(1-isopropylpyrrolidin-3-yl) oxime 
• 912947-12-7 4-(1-Isopropyl-pyrrolidin-3-yloxy)-benzonitrile 

Relevant academic research and scientific papers

Preparation method of N-substituent-3-hydroxytetrahydropyrrole

The invention discloses a preparation method of N-substituent-3-hydroxytetrahydropyrrole. The preparation method takes 1,2,4-butanetriol as a starting material, and comprises the following steps: performing a halogenating reaction between the starting material and hydrogen halide to prepare an intermediate 1,4-dihalogeno-2-butanol first, and then performing a condensation reaction with primary amine RNH2 to obtain a target product, wherein R represents methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, tertiary butyl or benzyl; the halogenating reaction is performed in the presence of an acidic catalyst, and the acidic catalyst is formic acid or acetic acid; and hydrogen halide is hydrogen chloride or hydrogen bromide. The preparation method disclosed by the invention is relatively short in synthetic route, the starting material 1,2,4-butanetriol is low in price and easy to obtain, and other materials used in the method are relatively high in safety and also relatively low in price, so that the preparation method is suitable for industrial large-scale production. Particularly, the halogenating reaction can obtain a yield of 50% or above by selection of suitable halogenating agents and catalysts.

Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors

The synthesis and in vitro activities of a series of succinyl-nitrile-based inhibitors of Cathepsin S are described. Several members of this class show nanomolar inhibition of the target enzyme as well as cellular potency. The inhibitors displaying the greatest potency contain N-alkyl substituted piperidine and pyrrolidine rings spiro-fused to the α-carbon of the P1 residue.