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2420-56-6 Usage


Conjugated linoleic acid (CLA) is a group of 8 geometric isomers of linoleic acid, characterized by two contiguous double bonds. It is primarily found in meat and dairy products, with the predominant isomer in animal tissue being 9Z,11E, and smaller amounts of 10E,12Z also present. CLA has been associated with various health benefits, including antioxidant and antitumor activities, which are believed to be due to competitive inhibition of Δ6-desaturase and/or PPARγ activation.


Used in the Beauty Products Industry:
Conjugated linoleic acid is used as an ingredient in beauty products for its anti-inflammatory, acne reductive, and moisture-retentive properties when applied topically on the skin. It is particularly popular for its beneficial effects on skin health.
Used in the Pharmaceutical Industry:
Conjugated linoleic acid is used as a potential therapeutic agent due to its various antioxidant and antitumor activities. These activities have been attributed to its ability to inhibit Δ6-desaturase and/or activate PPARγ, which may contribute to the reported health benefits of dietary supplementation with CLA.
Used in the Nutritional Supplements Industry:
As a dietary supplement, CLA is used to provide the reported health benefits associated with its consumption, such as improved immune function, reduced body fat, and enhanced muscle growth. It is often marketed as a weight management and sports performance supplement.

Check Digit Verification of cas no

The CAS Registry Mumber 2420-56-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,2 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2420-56:
56 % 10 = 6
So 2420-56-6 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017


1.1 GHS Product identifier

Product name 10(E),12(Z)-Conjugated Linoleic Acid

1.2 Other means of identification

Product number -
Other names T10C12 Cla

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2420-56-6 SDS

2420-56-6Relevant articles and documents

Synergetic effect of ruthenium and basicity sites in the Ru-MgAl catalyst for hydrogen-free production of conjugated linoleic acids

Chen, Jiebo,Chen, Xinxiang,Zheng, Ying,Li, Qinglu

, p. 20248 - 20255 (2015/03/18)

A series of Ru-MgAl composite oxide catalysts prepared by calcining the ruthenium grafted hydrotalcite-like precursor at various temperatures were used in the hydrogen-free production of conjugated linoleic acid. The effect of calcination temperature on the textural, base and catalytic properties of the materials was investigated. Results indicated that the Ru-MgAl composite oxides calcined at 450 °C showed high activity, namely, CLA productivity, CLA production rate and TOF up to 1.52 g CLA g (CLA) L-1 (solvent) min-1, 284 g (CLA) g-1 (Ru) h-1 and 102.6 mol (LA converted) mol-1 (Ru) h-1. Moreover, the biologically active CLA isomers, cis-9, trans-11, trans-10, cis-12 and trans-9, trans-11-CLA, were the main products, while almost no hydrogenated products were formed. Meanwhile, the role of ruthenium and basicity sites in the catalytic reaction has been studied. It was found that the basicity sites of the Ru-MgAl catalyst and the ruthenium activity sites seem to have a synergic effect on the catalytic reaction. The possible reaction mechanism for the isomerization was also proposed. This journal is

Method For The Production Of Conjugated Polyunsaturated Fatty Acids With Heterogenous Catalysts


Paragraph 0105, (2013/09/26)

The present invention relates to an improved process for the production of conjugated polyunsaturated fatty acids (PUFA), preferably conjugated linoleic acid (CLA), using finely dispersed heterogeneous metal catalysts on a mesoporous support, in the absence of Hg. The present invention also relates to a method to increase the large microporosity and (optionally) the small mesoporosity of a zeolite, thus obtaining a modified zeolite having a large and highly accessible internal surface.

Sustainable and efficient methodology for CLA synthesis and identification

Moreno, Maria,Gomez, M. Victoria,Cebrian, Cristina,Prieto, Pilar,De La Hoz, Antonio,Moreno, Andres

, p. 2584 - 2594 (2013/02/23)

Microwave-assisted organic synthesis and continuous-flow techniques have been successfully employed for the preparation of conjugated linoleic acids (CLA), compounds with high health beneficial effects. A good production rate of CLA was obtained. A sustainable methodology for the differentiation of both positional and geometrical CLA isomers (diene), based on the analysis by NMR spectroscopy of the resulting Diels-Alder cycloadducts with an appropriate dienophile, was developed.

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