24202-79-7

Usage

Uses

Used in Pharmaceutical Industry:
3-(Methoxycarbonyl)isonicotinic acid is used as a key intermediate for the production of various drugs and pharmaceuticals. Its unique chemical structure allows it to be incorporated into the synthesis of complex organic molecules, contributing to the development of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 3-(Methoxycarbonyl)isonicotinic acid serves as a building block for the formation of complex organic molecules. Its versatile chemical properties enable it to be used in the creation of a wide range of organic compounds, expanding the scope of chemical research and applications.
Used in Medicinal Chemistry:
3-(Methoxycarbonyl)isonicotinic acid is an important compound in medicinal chemistry, where it is utilized in the design and synthesis of new drug candidates. Its unique structure and reactivity make it a valuable component in the development of innovative pharmaceuticals with potential therapeutic benefits.

Upstream product

• 67-56-1 methanol 
• 4664-08-8 cinchomeronic anhydride 
• 490-11-9 3,4-pyridinecarboxylic acid 
• 1796-83-4 dimethyl 3,4-pyridinedicarboxylate 

Downstream Products

• 81113-13-5 3-Hydroxymethyl-isonicotinic acid 
• 110-86-1 pyridine 
• 93-60-7 methyl 3-pyridinecarboxylate 
• 490-11-9 3,4-pyridinecarboxylic acid 
• 24202-74-2 4-(methoxycarbonyl)nicotinic acid 

Relevant academic research and scientific papers

NON-PEPTIDE OPIOID RECEPTOR MODULATORS

Non-peptide MOR opioid receptor modulators are provided. The compounds exhibit predominantly central activity and are used to treat e.g. opioid addiction. The compounds described herein are generally delivered (administered) in a pharmaceutical compositio

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Design, Synthesis, and Biological Evaluation of the Third Generation 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4′-pyridyl)carboxamido]morphinan (NAP) Derivatives as μ/κ Opioid Receptor Dual Selective Ligands

μ opioid receptor (MOR) agonists have been widely applied for treating moderate to severe pain. However, numerous adverse effects have been associated with their application, including opioid-induced constipation (OIC), respiratory depression, and addicti

Synthesis of 11-Amino-substituted-9-methoxy-5-methyl-6H-pyridocarbazoles

A route to 11-amino-substituted-6H-pyridocarbazoles has been studied.Thus, condensation of 2-(4-lithiopyridine-3-yl)-4,4-dimethyloxazoline with 2-acetyl-5-methoxy-1-phenylsulphonylindole led to a low yield of the expected alcohol, which upon hydrolysis gave a complex mixture.A better starting building block was 4-acetyl-N,N-diisopropylnicotinamide obtained either from N,N-diisopropyl-4-lithionicotinamide (low yield) or from pyridine-3,4-dicarboxylic anhydride, using a 4-step sequence.This compound was treated with 2-lithio-5-methoxy-1-phenylsulphonylindole, affording N,N-diisopropyl-4-nicotinamide.Hydrolysis and then reduction led to 4-nicotinic acid whose amides were cyclized by phosphorus trichlorideoxide.Finally, the title compounds were obtained by Raney-nickel reduction-elimination of the 6-phenylsulphonyl protecting group.

Synthesis of the Pyridine Analogues of Phthalide

Routes for the preparation of the four isomeric pyridine analogues of phthalide are described starting from the readily available pyridine 2,3- and 3,4-diacids, or derivatives, and making use of the differential reactivity of substituents at pyridine 2- versus 3- and 3- versus 4-positions.