24221-38-3

Upstream product

• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 2138-33-2 3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one 
• 2125-49-7 3-dimethylamino-1-(4-methoxy-phenyl)-propan-1-one; hydrochloride 

Downstream Products

• 1346460-74-9 3-(4-methoxyphenyl)-N,N-dimethyl-3-morpholinopropan-1-amine hydrochloride 
• 88384-31-0 Carbonic acid 3-dimethylamino-1-(4-methoxy-phenyl)-propyl ester phenyl ester; hydrochloride 

Relevant academic research and scientific papers

ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANT

Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al.

Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake.

A series of naphthalenyloxy-arylpropylamines have been prepared and are demonstrated to be inhibitors of both serotonin and norepinephrine reuptake. One member of this series, duloxetine (Cymbalta) has proven to be effective in clinical trials for the treatment of depression.