24222-51-3

Basic information

• Product Name: (4aR,8aS)-5,5,8a-trimethyldecalin-2-one
• Synonyms: (4aR,8aS)-5,5,8a-Trimethyloctahydronaphthalen-2(1H)-one; 2(1H)-naphthalenone, octahydro-5,5,8a-trimethyl-, (4aR,8aS)-
• CAS NO: 24222-51-3
• Molecular Formula: C₁₃H₂₂O
• Molecular Weight: 194.31
• Mol File: 24222-51-3.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 260.2°C at 760 mmHg
• Flash Point: 103.8°C
• Density: 0.933g/cm³
• Vapor Pressure: 0.0124mmHg at 25°C
• Refractive Index: 1.471
• CAS DataBase Reference: (4aR,8aS)-5,5,8a-trimethyldecalin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,8aS)-5,5,8a-trimethyldecalin-2-one(24222-51-3)
• EPA Substance Registry System: (4aR,8aS)-5,5,8a-trimethyldecalin-2-one(24222-51-3)

Safety Data

• Hazardous Substances Data: 24222-51-3(Hazardous Substances Data)

Upstream product

• 14506-67-3 15,16,17-trinorlabdane-8,13-dione 
• 58239-51-3 (2S,4aS,8aR)-1,2α,3,4,4aα,5,6,7,8,8aβ-decahydro-5,5,8aβ-trimethyl-2β-naphthalenol 
• 24238-83-3 1,7,7-trimethyl-bicyclo[4.4.0]decan-3-ol 
• 71886-86-7 4,4a,5,6,7,8-hexahydro-5,5-dimethyl-2(3H)-naphthalenone 
• 112572-62-0 (-)-(4aR,8aR)-3,4,4a,5,6,7,8,8a-octahydro-4a,8,8-trimethylnaphthalene-2(1H)-one 
• 190523-56-9 (4a'R,6'S,8a'R)-(+)-5',5',8a'-trimethyloctahydrospiro(1,3-dioxolane-2,2'-(1'H)-naphthalen)-6'-yl N,N,N',N'-tetramethylphosphorodiamidate 
• 146276-81-5 (+)-(5S,10S)-(9S)-7-drimene-11,12-diol 
• 807360-62-9 (1S,8aR)-2-acetyloxy-5,5,8a-trimethyl-1,5,6,7,8,8a-hexahydro-naphthalene-1-carboxylic acid (-)-menthyl ester 
• 807360-57-2 3-acetyloxy-5-(2',6',6'-trimethylcyclohex-1'-enyl)-penta-2,4-dienoic acid (-)-menthyl ester 
• 807360-71-0 (1R,4aS,8aS)-5,5,8a-trimethyl-2-oxo-decahydro-naphthalene-1-carboxylic acid (-)-menthyl ester 
• 807360-99-2 (1R,4aS,8aS)-5,5,8a-trimethyl-2-oxo-decahydro-naphthalene-1-carboxylic acid benzyl ester 
• 204326-12-5 (-)-11-hydroxy-(9R)-12-nordriman-8-one 
• 190523-58-1 (-)-[4aR,8aS]-1,1',8a-trimethyloctahydro-6,6'-(1,3-dioxolane)-naphthalene 
• 143245-70-9 (+)-(4aR,8aS)-3(E)-benzylidene-3,4,4a,5,6,7,8,8a-octahydro-4a,8,8-trimethyl-naphthalen-2(1H)-one 

Relevant articles and documents

An efficient approach to chiral nonracemic trans- and cis-decalin scaffolds for drimane and labdane synthesis

Optically active trans- and cis-ring junction decalinic intermediates, which represent useful precursors for the synthesis of more complex natural targets, have been conveniently prepared starting from the β-ketoester 2 obtained by standard chemistry from

NOVEL 1H- SPIRO [NAPHTALENE- 2, 2 ' -OXIRANE] DERIVATIVES

Compounds of formula (I), wherein R1 is hydrogen, methyl or ethyl, and R2 is methyl or ethyl, having woody and ambery odor notes, their use as fragrance ingredient and perfumed products comprising them.

Enantioselective syntheses of (2S,4AS,8aR)-1,1-4a-trimethyldecahydronaphthalen-2-ol[(-)-TMD], (4aS,8aR)-5,58a-trimethyloctahydronaphthalen-2(1H)-one, and (-)-Polywood, through Michael-type reaction of chiral imines

The title compounds 6, 15, and 17 have been synthesized in a straightforward way in good yields and high enantiomeric excesses by the chiral imines method, leading to building-blocks 2 and 10, followed by a few conventional steps.