24242-97-5

Basic information

• Product Name: 1-(4-isobutoxyphenyl)ethanone
• Synonyms: 1-(4-isobutoxyphenyl)ethanone;1-(4-isobutoxyphenyl)ethanone(SALTDATA: FREE)
• CAS NO: 24242-97-5
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.26
• Mol File: 24242-97-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 297.8°C at 760 mmHg
• Flash Point: 124.9°C
• Appearance: /
• Density: 0.986g/cm³
• Vapor Pressure: 0.00132mmHg at 25°C
• Refractive Index: 1.494
• CAS DataBase Reference: 1-(4-isobutoxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-isobutoxyphenyl)ethanone(24242-97-5)
• EPA Substance Registry System: 1-(4-isobutoxyphenyl)ethanone(24242-97-5)

Safety Data

• Hazardous Substances Data: 24242-97-5(Hazardous Substances Data)

Usage

General Description

1-(4-isobutoxyphenyl)ethanone is a chemical compound with the molecular formula C12H16O2. It is a ketone derivative with a structure consisting of a phenyl ring substituted with an isobutyl group and a carbonyl group. This chemical is commonly used in the production of various fragrances and flavors due to its pleasant odor. It is also utilized in the manufacturing of pharmaceuticals and as a solvent in organic synthesis. Additionally, 1-(4-isobutoxyphenyl)ethanone has potential applications in the field of organic electronics and as a reagent in chemical reactions. However, it is essential to handle this compound with care as it may be hazardous if not used properly.

InChI:InChI=1/C12H16O2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13/h4-7,9H,8H2,1-3H3

Upstream product

• 1126-75-6 (isobutyloxy)benzene 
• 108-24-7 acetic anhydride 
• 78-77-3 Isobutyl bromide 
• 99-93-4 4-Hydroxyacetophenone 

Downstream Products

• 1574394-72-1 ethyl 3-(4-isobutoxyphenyl)-3-oxopropanoate 
• 308143-24-0 3-fluoro-4-(2-fluorobenzyl)2-[4-(2-methylpropyloxy)phenyl]-6-(ethyloxycarbonyl)pyrrolo[1,2-a]pyrimid-7-one 
• 308143-22-8 2-fluoromethyl-1-[2-(4-isobutoxy-phenyl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 308143-23-9 3-fluoro-2-[4-(2-methylpropyloxy)phenyl]-6-(ethyloxycarbonyl)pyrrolo[1,2-a]pyrimid-7-one 
• 53704-76-0 α-bromo-4'-isobutoxyacetophenone 
• 78382-11-3 C₁₃H₂₀N₄OS 
• 63957-29-9 1-(4-isobutoxy-phenyl)-3-piperidino-propan-1-one; hydrochloride 

Relevant articles and documents

HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase

The identification of novel, non-purine based inhibitors of xanthine oxidase is described. After a high-throughput screening campaign, an NMR based counterscreen was used to distinguish actives, which interact with XO in a reversible manner, from assay artefacts. This approach identified pyrimidone 1 as a reversible and competitive inhibitor with good lead-like properties. A hit to lead campaign gave compound 41, a nanomolar inhibitor of hXO with efficacy in the hyperuricemic rat model after oral dosing.

Catalytic Friedel-Crafts acylation of alkoxy benzenes by ferric hydrogensulfate

Friedel-Crafts acylation of alkoxy benzenes is achieved efficiently by reaction with aliphatic acid anhydrides in the presence of catalytic amounts of ferric hydrogensulfate, Fe(HSO4)3, in nitromethane. Alkyl benzenes and aryl halides, as well as aromatic anhydrides, remain intact under these conditions.

Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein Ar, B, R1, R2, R3a, R3b, R4, R5, R6and m are as defined herein.