1126-75-6

Basic information

• Product Name: (2-methylpropoxy)benzene
• Synonyms: Benzene, (2-methylpropoxy)-; Ether, isobutyl phenyl; Isobutyl phenyl ether
• CAS NO: 1126-75-6
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.2176
• Mol File: 1126-75-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 196°C at 760 mmHg
• Flash Point: 71.6°C
• Density: 0.919g/cm³
• Vapor Pressure: 0.572mmHg at 25°C
• Refractive Index: 1.484
• CAS DataBase Reference: (2-methylpropoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methylpropoxy)benzene(1126-75-6)
• EPA Substance Registry System: (2-methylpropoxy)benzene(1126-75-6)

Safety Data

• Hazardous Substances Data: 1126-75-6(Hazardous Substances Data)

Usage

Description

(2-methylpropoxy)benzene, also known as isobutylbenzene, is a colorless liquid chemical compound with the molecular formula C10H14. It possesses a sweet, floral odor and is commonly utilized in various industrial applications.

Uses

Used in Industrial Cleaners:
(2-methylpropoxy)benzene is used as a solvent in the production of industrial cleaners due to its ability to dissolve a wide range of substances, making it effective in removing dirt and stains.
Used in Perfumes and Personal Care Products:
(2-methylpropoxy)benzene is used as a fragrance ingredient in perfumes and personal care products, providing a sweet, floral scent that enhances the overall aroma of these products.

Upstream product

• 5820-22-4 methylallyl phenyl ether 
• 462-06-6 fluorobenzene 
• 78-83-1 2-methyl-propan-1-ol 
• 621-87-4 3-phenoxy-2-propanone 
• 31729-70-1 bis(iodozinc)methane 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 108-94-1 cyclohexanone 
• 139-02-6 sodium phenoxide 
• 513-38-2 Isobutyl iodide 
• 108-95-2 phenol 
• 78-77-3 Isobutyl bromide 

Downstream Products

• 87299-24-9 4-isobutoxy-deoxybenzoin 
• 15560-74-4 (4-Isobutoxy-phenyl)-acetic acid ethyl ester 
• 139-02-6 sodium phenoxide 
• 14794-52-6 N-hydroxy-2-(4-isobutoxyphenyl)acetamide 
• 1160-69-6 2-<4-Isobutyloxy-phenylmercaptomethyl>-benzoesaeure 
• 64360-34-5 [4-(4-Isobutoxy-benzyloxy)-phenyl]-acetic acid 
• 60736-76-7 3-chloro-4-(4'-isobutoxybenzyloxy)-phenylacetic acid 
• 1138-54-1 4-(iso-butoxy)-phenylsulfonyl chloride 
• 18962-07-7 4-isobutoxybenzaldehyde 
• 874204-71-4 methyl 3-[2-isobutoxy-5-(4-isobutoxybenzoyl)phenyl]propionate 
• 354539-62-1 1-(4-isobutoxy-phenyl)-propan-1-one 

Relevant articles and documents

Radiosynthesis of 1-iodo-2-[11C]methylpropane and 2-methyl-1-[11C]propanol and its application for alkylation reactions and C―C bond formation

The multitude of biologically active compounds requires the availability of a broad spectrum of radiolabeled synthons for the development of positron emission tomography (PET) tracers. The aim of this study was to synthesize 1-iodo-2-[11C]methylpropane and 2-methyl-1-[11C]propanol and investigate the use of these reagents in further radiosynthesis reactions. 2-Methyl-1-[11C]propanol was obtained with an average radiochemical yield of 46?±?6% d.c. and used with fluorobenzene as starting material. High conversion rates of 85?±?4% d.c. could be observed with HPLC, but large precursor amounts (32?mg, 333?μmol) were needed. 1-Iodo-2-[11C]methylpropane was synthesized with a radiochemical yield of 25?±?7% d.c. and with a radiochemical purity of 78?±?7% d.c. The labelling agent 1-iodo-2-[11C]methylpropane was coupled to thiophenol, phenol and phenylmagnesium bromide. Average radiochemical conversions of 83% d.c. for thiophenol, 40% d.c. for phenol, and 60% d.c. for phenylmagnesium bromide were obtained. In addition, [11C]2-methyl-1-propyl phenyl sulphide was isolated with a radiochemical yield of 5?±?1% d.c. and a molar activity of 346?±?113?GBq/μmol at the end of synthesis. Altogether, the syntheses of 1-iodo-2-[11C]methylpropane and 2-methyl-1-[11C]propanol were achieved and applied as proof of their applicability.

Domino Methylenation/Hydrogenation of Aldehydes and Ketones by Combining Matsubara's Reagent and Wilkinson's Catalyst

The methylenation/hydrogenation cascade reaction of aldehydes or ketones through a domino process involving two ensuing steps in a single pot is realized. The compatibility of Matsubara's reagent and Wilkinson's complex give a combination that allows, under dihydrogen, the transformation of a carbonyl function into a methyl group. This new method is suitable to introduce an ethyl motif from aromatic and aliphatic aldehydes with total chemoselectivity and total retention of α-stereochemical purity. The developed procedure is also extended to the introduction of methyl groups from ketones.

Heterogeneous palladium-catalyzed synthesis of aromatic ethers by solvent-free dehydrogenative aromatization: Mechanism, scope, and limitations under aerobic and non-aerobic conditions

Starting from cyclohexanone derivatives and alcohols, both non-aromatic precursors, aryl ethers could be synthesized in good yields and with good selectivities in the presence of a catalytic amount of Pd/C, in one step, without added solvent, in a reaction vessel open to air. For less reactive substrates, the addition of 1-octene in a closed system under non-aerobic conditions improved the conversion. In addition, the catalyst could be recycled several times with no decrease in the yield of the aryl ether. The process was also used with tetralone derivatives and polyols. Several reactions were performed to propose a mechanism for this transformation. The formation of an enol ether followed by a dehydrogenation reaction seem to be the key steps of this reaction. Aryl ethers were prepared in good yields and with good selectivities in a solvent-free and heterogeneous catalytic dehydrogenative alkylation of cyclohexanones with various alcohols. Three different complementary routes were used, and for the first time, non-aerobic, safe conditions could be used. Moreover, the catalyst could be recycled several times with no decrease in the yield of the aryl ether. Copyright