242459-83-2 Usage
Uses
Used in Pharmaceutical Industry:
Benzyl 3-((chlorosulfonyl)methyl)piperidine-1-carboxylate is used as a reactant for the preparation of oxadiazolyl piperidine derivatives. These derivatives serve as rotamase enzyme inhibitors, which are crucial in the treatment of neurological disorders arising from neurodegenerative diseases and nerve damage. The compound's role in this application is to provide a structural foundation for the development of inhibitors that can target and modulate the activity of rotamase enzymes, thereby potentially alleviating the symptoms and progression of related neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 242459-83-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,2,4,5 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 242459-83:
(8*2)+(7*4)+(6*2)+(5*4)+(4*5)+(3*9)+(2*8)+(1*3)=142
142 % 10 = 2
So 242459-83-2 is a valid CAS Registry Number.
242459-83-2Relevant academic research and scientific papers
A library of conformationally restricted saturated heterocyclic sulfonyl chlorides
Zhersh, Sergey,Buryanov, Volodymyr V.,Karpenko, Oleksandr V.,Grygorenko, Oleksandr O.,Tolmachev, Andrey A.
, p. 3669 - 3674 (2011/12/16)
An approach to the synthesis of conformationally restricted saturated heterocyclic sulfonyl chlorides is described. Being guided by the principle of diversity-oriented conformational restriction, a mini-library of saturated heterocyclic sulfonyl chlorides
Heterocyclic compounds as inhibitors of rotomase enzymes
-
, (2008/06/13)
Compounds of the formula: wherein R1, Y, W, A and R2are as defined above are inhibitors of rotamase enzymes in particular FKBP-12 and FKBP-52. The compounds therefore moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage.
