242481-20-5

Basic information

• Product Name: 3-amino-4-imino-8,8-dimethyl-5-(4-chlorophenyl)-3,4,5,6,7,9-hexahydro-8H-6-oxo-chromeno[2,3-d]pyrimidine
• Synonyms: 3-amino-4-imino-8,8-dimethyl-5-(4-chlorophenyl)-3,4,5,6,7,9-hexahydro-8H-6-oxo-chromeno[2,3-d]pyrimidine
• CAS NO: 242481-20-5
• Molecular Weight: 370.838
• Mol File: 242481-20-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-amino-4-imino-8,8-dimethyl-5-(4-chlorophenyl)-3,4,5,6,7,9-hexahydro-8H-6-oxo-chromeno[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-4-imino-8,8-dimethyl-5-(4-chlorophenyl)-3,4,5,6,7,9-hexahydro-8H-6-oxo-chromeno[2,3-d]pyrimidine(242481-20-5)
• EPA Substance Registry System: 3-amino-4-imino-8,8-dimethyl-5-(4-chlorophenyl)-3,4,5,6,7,9-hexahydro-8H-6-oxo-chromeno[2,3-d]pyrimidine(242481-20-5)

Safety Data

• Hazardous Substances Data: 242481-20-5(Hazardous Substances Data)

Upstream product

• 242481-12-5 ethyl N-(4-(4-chlorophenyl)-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-2-yl)formimidate 
• 107753-00-4 2-amino-4-(4-chlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 
• 242481-16-9 4-imino-8,8-dimethyl-5-(4-chlorophenyl)-3-benzyl-3,4,5,6,7,9-hexahydro-8H-6-oxo-chromeno[2,3-d]pyrimidine 

Relevant articles and documents

Utility of 2-amino-4,5,6,8-tetrahydro-7H-chromene-3-carbonitriles in synthesis of chromeno[2,3-d]pyrimidine and chromeno[3,2-e] [1,2,4]triazolo[1,5-c]pyrimidine derivatives of pharmaceutical interest

Chromeno[2,3-d]pyrimidines (5, 6 and 8) have been prepared by the reaction of 2-amino-7,7-dimethyl-4-substitutedphenyl-5-oxo-4,5,6,8-tetrahydro-7H-chromene-3- carbonitriles (2a,b) with formic acid, form amide and phenyl isothiocyanate respectively. The reaction of 3-amino-4-iminochromeno[2,3-d]pyrimidine (11) with formic acid, acetic anhydride and p-chlorobenzaldehyde have furnished the chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines (12, 14 and 15) respectively.