24255-25-2

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Morpholinopyridine 96 is used as an intermediate compound for the synthesis of various pharmaceutical products. Its presence in the molecular structure allows for the creation of new drug molecules with potential therapeutic applications.
Used in Chemical Product Synthesis:
2-Morpholinopyridine 96 is used as a key component in the production of different chemical products. Its unique properties contribute to the development of novel compounds with specific functions and applications in various industries.
Used in Research and Development:
2-Morpholinopyridine 96 is employed as a research compound in the field of chemistry and material science. It aids in understanding the behavior of molecules and their interactions, which can lead to the discovery of new materials and technologies.

Upstream product

• 110-91-8 morpholine 
• 2402-78-0 2,6-dichloropyridine 
• 372-48-5 2-fluoropyridine 
• 904326-93-8 [6-(morpholin-4-yl)pyridin-3-yl]boronic acid 
• 109-04-6 2-bromo-pyridine 

Relevant academic research and scientific papers

Magnesium-mediated arylation of amines via C-F bond activation of fluoroarenes

A series of new Mg(ii) amides featuring a bulky β-diketiminate backstop ligand, has been synthesised. These complexes are demonstrated to be excellent sources of nucleophilic amides that can participate in rapid C-F activation of several fluoroarenes at room temperature or using microwave assistance, leading to the installment of synthetically important C-N bonds via nucleophilic substitution.

Nitrosation of aryl and heteroaryltrifluoroborates with nitrosonium tetrafluoroborate

Organotrifluoroborates have emerged as an alternative to toxic and air- and moisture-sensitive organometallic species for the synthesis of functionalized aryl and heteroaryl compounds. It has been shown that the trifluoroborate moiety can be easily converted into a variety of different substituents in a late synthetic stage. In this paper, we disclose a mild, selective, and convenient method for the ipso-nitrosation of organotrifluoroborates using nitrosonium tetrafluoroborate (NOBF4). Aryl- and heteroaryltrifluoroborates were converted into the corresponding nitroso products in good to excellent yields. This method proved to be tolerant of a broad range of functional groups.

Palladium-catalysed amination of halopyridines on a KF-alumina surface

Palladium-catalysed C-N hetero cross-coupling reactions between bromopyridines and amines (both primary and secondary) can be efficiently performed on a KF-alumina (basic) surface, thus negating the use of strong bases such as sodium tert-butoxide. The reaction conditions are optimised with reference to catalytic systems, solvents and the surface.

Nickel-mediated amination chemistry. Part 1: Efficient aminations of (het)aryl 1,3-di and 1,3,5-trichlorides

The first Ni-catalysed synthesis of di- and triamino substituted benzenes and diamino substituted pyridines from the corresponding aryl chlorides and amines is described. (C) 2000 Elsevier Science Ltd.