24255-25-2

Basic information

• Product Name: 2-MORPHOLINOPYRIDINE 96
• Synonyms: 2-MORPHOLINOPYRIDINE 96;4-(pyridin-2-yl)Morpholine;2-(4-Morpholinyl)pyridine, 96%
• CAS NO: 24255-25-2
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.207
• Product Categories: Heterocyclic Compounds;C9 to C46;Heterocyclic Building Blocks;Pyridines;Building Blocks;C8 to C9;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 24255-25-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 135 °C20 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /Liquid
• Density: 1.131
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 5.57±0.10(Predicted)
• CAS DataBase Reference: 2-MORPHOLINOPYRIDINE 96(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MORPHOLINOPYRIDINE 96(24255-25-2)
• EPA Substance Registry System: 2-MORPHOLINOPYRIDINE 96(24255-25-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 24255-25-2(Hazardous Substances Data)

Usage

General Description

2-Morpholinopyridine 96 is a chemical compound that is often used in the synthesis of various pharmaceutical and chemical products. It has the molecular formula C9H11N3O, showcasing the presence of carbon, hydrogen, nitrogen, and oxygen atoms in its structure. As suggested by its name, this compound has a purity level of 96%, indicating a high grade. It has distinct properties and, like any chemical, should be handled with care to ensure safety. The exact nature of its function can vary depending on its use in different chemical reactions and processes.

Upstream product

• 110-91-8 morpholine 
• 2402-78-0 2,6-dichloropyridine 
• 372-48-5 2-fluoropyridine 
• 904326-93-8 [6-(morpholin-4-yl)pyridin-3-yl]boronic acid 
• 109-04-6 2-bromo-pyridine 

Relevant articles and documents

Magnesium-mediated arylation of amines via C-F bond activation of fluoroarenes

A series of new Mg(ii) amides featuring a bulky β-diketiminate backstop ligand, has been synthesised. These complexes are demonstrated to be excellent sources of nucleophilic amides that can participate in rapid C-F activation of several fluoroarenes at room temperature or using microwave assistance, leading to the installment of synthetically important C-N bonds via nucleophilic substitution.

Palladium-catalysed amination of halopyridines on a KF-alumina surface

Palladium-catalysed C-N hetero cross-coupling reactions between bromopyridines and amines (both primary and secondary) can be efficiently performed on a KF-alumina (basic) surface, thus negating the use of strong bases such as sodium tert-butoxide. The reaction conditions are optimised with reference to catalytic systems, solvents and the surface.