24262-65-5

Upstream product

• 2345-34-8 4-acetyloxy-benzoic acid 
• 98-80-6 phenylboronic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 108-95-2 phenol 
• 27914-73-4 4-acetoxybenzoyl chloride 
• 17696-62-7 Phenyl 4-hydroxybenzoate 
• 108-24-7 acetic anhydride 

Downstream Products

• 17696-62-7 Phenyl 4-hydroxybenzoate 
• 1108157-34-1 4,4’-bis(hexylphenyl)benzophenone 

Relevant academic research and scientific papers

Cu(II)-silsesquioxanes as efficient precatalysts for Chan-Evans-Lam coupling

Two cage copper(II)silsesquioxanes, namely, tricopper complex (PhSiO1.5)8(CuO)3(TMEDA)2*(MeCN)3 Cu-1 and hexacopper complex (MeSiO1,5)12(CuO)6(Py)6*TMEDA Cu

Synthetic method for ultraviolet absorbent namely 4,4'-dihexyloxybenzophenone

The invention discloses a synthetic method for an ultraviolet absorbent namely 4,4'-dihexyloxybenzophenone. The method comprises the following steps: with p-hydroxybenzoic acid as a starting material, carrying out acetylation to protect hydroxy; carrying out a Fredel-Crafts reaction of p-acetoxybenzoic acid and phenol under the catalysis of zinc chloride and phosphorus oxychloride so as to synthesize an intermediate namely phenyl p-hydroxybenzoate; then carrying out deacetylation to remove the protective group, and carrying out Fries rearrangement so as to prepare an intermediate namely 4,4-dihydroxybenzophenone; and forming a salt with 4,4-dihydroxybenzophenone and potassium carbonate, and carrying out a Williamson reaction of 1-bromohexane and the potassium salt of 4,4-dihydroxybenzophenone through catalysis of tetrabutylammonium bromide so as to synthesize the 4,4'-dihexyloxybenzophenone. The synthetic method provided by the invention has the advantages of mild reaction conditions, normal pressure, medium and low temperature, stable quality control, high raw material conversion rate, effective inhibition of side reactions, fewer three wastes, light pollution, and facilitation of protecting the environment and labor of a producer.

Enzymatic hydrolyses of acetoxy- and phenethylbenzoates by Candida cylindracea lipase

The lipase from Candida cylindracea (CCL) deacctyles rapidly and selective all three regioisomer methyl acctoxybenzoates. In the enzymatic hydrolyses of analogous aryl acctoxybenzoates, the difference of reactivity between the acetoxy and benzoloxy funcionalities is reduced and a aspirin- like prodrugs. The degree of enantioselectivity of the enzymatic hydrolysis of phenethylbenzoates is related to the position of the stereogenic center.