24280-45-3

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl piperazine-1-carboxylate monohydrochloride is used as a precursor in the synthesis of various drugs, including antihistamines and antipsychotic medications, due to its ability to contribute to the development of these therapeutic agents.
Used in Organic Synthesis:
ethyl piperazine-1-carboxylate monohydrochloride serves as a building block in the synthesis of organic compounds, playing a crucial role in the creation of new chemical entities with potential applications in various fields.
Used in Chemical Research:
Ethyl piperazine-1-carboxylate monohydrochloride is utilized as a reagent in chemical research, aiding scientists in understanding and advancing the knowledge of chemical reactions and processes involving piperazine-based compounds.

InChI:InChI=1/C7H14N2O2.ClH/c1-2-11-7(10)9-5-3-8-4-6-9;/h8H,2-6H2,1H3;1H

Upstream product

• 120-43-4 4-ethoxycarbonylpiperazine 
• 116-54-1 dichloroacetic acid methyl ester 
• 219509-82-7 tert-butyl 4-ethoxycarbonylpiperazine-1-carboxylate 

Downstream Products

• 99931-83-6 ethyl 4-(2-pirymidinyl)-1-piperazinecarboxylate 
• 63981-46-4 4,4'-methanediyl-bis-piperazine-1-carboxylic acid diethyl ester 
• 13919-78-3 1-(4-chlorophenyl)-3-[(N₄-ethoxycarbonyl)piperazyl]-1-oxo-propane hydrochloride 
• 55829-12-4 4-[cyano-(2,3,4-trimethoxy-phenyl)-methyl]-piperazine-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Photoredox-Catalyzed Addition of Carbamoyl Radicals to Olefins: A 1,4-Dihydropyridine Approach

Functionalization with C1-building blocks are key synthetic methods in organic synthesis. The low reactivity of the most abundant C1-molecule, carbon dioxide, makes alternative carboxylation reactions with CO2-surrogates especially important. We report a photoredox-catalyzed protocol for alkene carbamoylations. Readily accessible 4-carboxamido-Hantzsch esters serve as convenient starting materials that generate carbamoyl radicals upon visible light-mediated single-electron transfer. Addition to various alkenes proceeded with high levels of regio- and chemoselectivity.

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).

Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines

The present invention discloses aromatic heterocyclic derivatives and applications of the aromatic heterocyclic derivatives in medicines, and specifically provides a class of aromatic heterocyclic compounds or stereoisomers, geometric isomers, tautomers, racemic bodies, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the compounds. The present invention further discloses uses of the compounds or pharmaceutical compositions in drug preparation, wherein the drug is used for treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).