242808-86-2Relevant academic research and scientific papers
Chirality transfer from silicon to carbon via diastereoselective Simmons-Smith cyclopropanation of chiral alkenylsilanols
Yamamura, Yuichi,Toriyama, Fumihiko,Kondo, Tatsuhiro,Mori, Atsunori
, p. 13 - 15 (2002)
Simmons-Smith cyclopropanation of a chiral alkenylsilanol with CH2I2-Et2Zn proceeds diastereoselectively to give the corresponding cyclopropylsilanol product. Chirality transfer from silicon to the alkenyl carbons of the silicon substituent is observed. The stereochemistry of the obtained cyclopropylsilanol is confirmed by converting to cyclopropanol via Tamao oxidation.
Synthesis and optical resolution of novel chiral silanols
Mori, Atsunori,Toriyama, Fumihiko,Kajiro, Hiroshi,Hirabayashi, Kazunori,Nishihara, Yasushi,Hiyama, Tamejiro
, p. 549 - 550 (2007/10/03)
Silanols bearing an asymmetric center on silicon, methyl(2-phenylethenyl)(3,3,3-trifluoropropyl)silanol and methyl(phenyl)(vinyl)silanol are synthesized by alkylative cleavages of cyclic siloxanes with an organolithium. Optical resolution of their enantio
