243131-93-3

Upstream product

• 243131-89-7 2,5-anhydro-N-benzyloxycarbonyl-4,6-di-O-tert-butyldiphenylsilyl-2,5-imino-1,3-O-isopropylidene-D-glucitol 
• 501-53-1 benzyl chloroformate 
• 171613-15-3 2,5-anhydro-N-benzyloxycarbonyl-2,5-imino-1,3-O-isopropylidene-D-glucitol 
• 191851-89-5 2,5-anhydro-N-benzyloxycarbonyl-2,5-imino-D-glucitol 
• 132295-44-4 2,5-anhydro-2,5-imino-D-glucitol 

Downstream Products

• 243131-94-4 2,5-anhydro-1-deoxy-N-benzyloxycarbonyl-4,6-di-O-tert-butyldiphenylsilyl-1-iodo-2,5-imino-D-glucitol 
• 243131-98-8 2,5-anhydro-4,6-di-O-tert-butyldiphenylsilyl-1-deoxy-1-{[1-(hydroxymethyl)propyl]amino}-2,5-imino-D-glucitol 
• 243131-96-6 1-amino-2,5-anhydro-N-benzyloxycarbonyl-1-deoxy-4,6-di-O-tert-butyldiphenylsilyl-2,5-imino-D-glucitol 
• 243131-95-5 2,5-anhydro-1-azido-N-benzyloxycarbonyl-1-deoxy-4,6-di-O-tert-butyldiphenylsilyl-2,5-imino-D-glucitol 
• 243131-97-7 2,5-anhydro-N-benzyloxycarbonyl-4,6-di-O-tert-butyldiphenylsilyl-1-deoxy-1-{[1-(hydroxymethyl)propyl]amino}-2,5-imino-D-glucitol 

Relevant academic research and scientific papers

Ethambutol-sugar hybrids as potential inhibitors of mycobacterial cell-wall biosynthesis

Ethambutol is an established front-line agent for the treatment of tuberculosis, and is also active against Mycobacterium avium infection. However, this agent exhibits toxicity, and is considered to have low potency. The action of ethambutol on the mycoba

Homologated aza analogs of arabinose as antimycobacterial agents

A series of hydrolytically-stable aza analogs of arabinofuranose was prepared and evaluated against Mycobacterium tuberculosis and M. avium. The compounds were designed to mimic the putative arabinose donor involved in biogenesis of the essential cell wall polysaccharide, arabinogalactan. Though most compounds displayed little activity in cell culture, one compound showed significantly activity in infected macrophage models.