243137-96-4

Upstream product

• 1026827-53-1 3'-bromo-4-(dibromomethyl)benzophenone 
• 102092-51-3 3-bromo-4′-methylbenzophenone 
• 585-76-2 m-bromobenzoic acid 
• 1711-09-7 3-bromobenzoyl chloride 

Downstream Products

• 243137-94-2 5-{3-(4-cyanobenzoyl)phenylethynyl}-2'-deoxy-5'-O-(4,4'-dimethoxytrityl) uridine 
• 243137-98-6 4-(3-trimethylsilylethynylbenzoyl)benzonitrile 
• 214548-26-2 4-(3-ethynylbenzoyl)benzonitrile 

Relevant academic research and scientific papers

Development of a Rhodium(II)-Catalyzed Chemoselective C(sp3)-H Oxygenation

We report the first example of RhII-catalyzed chemoselective double C(sp3)-H oxygenation, which can directly transform various toluene derivatives into highly valuable aromatic aldehydes with great chemoselectivity and practicality. The critical combination of catalyst Rh(OAc)2, oxidant Selectfluor, and solvents of TFA/TFAA promises the successful delivery of the oxidation with satisfactory yields. A possible mechanism involving a unique carbene-Rh complex is proposed, and has been supported by both experiments and theoretical calculations.