24321-47-9Relevant academic research and scientific papers
Cardenolide Glycosides of the Asclepiadaceae. New Glycosides from Asclepias fruticosa and the Stereochemistry of Uscharin, Voruscharin and Calotoxin
Cheung, H. T. Andrew,Chiu, Fransis C. K.,Watson, Thomas R.,Wells, Robert J.
, p. 2827 - 2835 (2007/10/02)
Eight new cardenolide glycosides, 19-deoxyuscharin (1b), 4'β-hydroxygomphoside (1k), 3'-didehydrogomphoside (1d), 3'-epigomphoside (1e), 3'-epiafroside (2e), 3'-epigomphoside 3'-acetate (1f), 3'-didehydroafroside (2d), and 3'-epiafroside 3'-acetate (2f), have been isolated from Asclepias fruticosa R.Br.The structures of all new compounds were established by spectral comparisons with known compounds.The chirality of C-3' of uscharin (3b), voruscharin, and 19-deoxyuscharin (1b) is proposed to be S.By comparison with 4'β-hydroxygomphoside (1k), the β configuration of the 4'-hydroxy group of calotoxin (3k) (from Calotropis procera) has been established.
