24367-50-8

Usage

Uses

Used in Organic Synthesis:
3-(2-(pyridin-3-yl)disulfanyl)pyridine is used as a building block in organic synthesis for the creation of complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 3-(2-(pyridin-3-yl)disulfanyl)pyridine is used as a promising candidate for drug development. Studies have demonstrated its biological activity, suggesting potential therapeutic applications. Its ability to be modified and incorporated into various molecular frameworks makes it a valuable component in the design of new drugs.
Used in Materials Science:
3-(2-(pyridin-3-yl)disulfanyl)pyridine also finds applications in materials science. Its structural properties can be leveraged to develop new materials with specific characteristics, such as conductivity, stability, or reactivity, depending on the desired application.
Overall, 3-(2-(pyridin-3-yl)disulfanyl)pyridine is a versatile compound with broad applications across different industries, primarily due to its unique structure and demonstrated biological activity. Its potential in organic synthesis, pharmaceutical development, and materials science highlights its importance in modern scientific research and technological advancements.

Upstream product

• 1692-25-7 3-pyridylboronic acid 
• 1120-90-7 3-iodopyridine 
• 626-55-1 3-Bromopyridine 

Relevant academic research and scientific papers

Importance of a Fluorine Substituent for the Preparation of meta- and para-Pentafluoro-λ6-sulfanyl-Substituted Pyridines

Although there are ways to synthesize ortho-pentafluoro-λ6-sulfanyl (SF5) pyridines, meta- and para-SF5-substituted pyridines are rare. We disclose herein a general route for their synthesis. The fundamental synthetic approach is the same as reported methods for ortho-SF5-substituted pyridines and SF5-substituted arenes, that is, oxidative chlorotetrafluorination of the corresponding disulfides to give pyridylsulfur chlorotetrafluorides (SF4Cl-pyridines), followed by chloride/fluoride exchange with fluorides. However, the trick in this case is the presence on the pyridine ring of at least one fluorine atom, which is essential for the successful transformation of the disulfides into m-and p-SF5-pyridines. After enabling the synthesis of an SF5-substituted pyridine, ortho-F groups can be efficiently substituted by C, N, S, and O nucleophiles through an SNAr pathway. This methodology provides access to a variety of previously unavailable SF5-substituted pyridine building blocks.

A novel dual-nano assisted synthesis of symmetrical disulfides from aryl/alkyl halides

Here, we have reported a novel approach towards dual-nano assisted synthesis of disulfides from coupling of alkyl/aryl halides and sulfur nanoparticles. The indium oxide nanoparticles as catalyst expedite the conversion and sulfur nanoparticle notably enhances the miscibility, providing a faster, high yielding and cost-effective process in ethanol-water system. The method has synthetic advantages in terms of mild reaction framework, catalyst regeneration, and absence of any sulfide or polysulfide linkage as by-product leading to a column free synthesis. A variety of alkyl, aryl and heteroaryl symmetrical disulfides are obtained in good to excellent yields up to exceeding 98%.

Synthesis of disulfides and diselenides by copper-catalyzed coupling reactions in water

A simple and efficient protocol for copper-catalyzed coupling reactions between aryl halides and elemental sulfur or selenium has been developed. A variety of disulfides and diselenides can be obtained in moderate to excellent yields up to 96%. The Royal Society of Chemistry 2013.

Oxidative coupling of thiols in solution and under solvent-free conditions

A mild and efficient method for the oxidative coupling of thiols by ammonium dichromate in the presence of silica chloride and wet SiO2 in solution and under solvent free conditions is reported.