24377-95-5

Usage

Uses

Used in Pharmaceutical Industry:
3-chloro-4-methylbenzamide is used as a building block for the synthesis of various pharmaceuticals due to its unique chemical structure and properties. It contributes to the development of new drugs and medicines.
Used in Agrochemical Industry:
In the agrochemical industry, 3-chloro-4-methylbenzamide is used as a building block for the synthesis of various agrochemicals. Its properties make it suitable for the development of new pesticides and other agricultural chemicals.
Used in Organic Chemistry:
3-chloro-4-methylbenzamide is used as a reagent in organic chemistry. Its unique structure allows it to participate in various chemical reactions, aiding in the synthesis of complex organic compounds.
Used in Dye and Pigment Production:
As an intermediate in the production of dyes and pigments, 3-chloro-4-methylbenzamide plays a crucial role in the development of new colorants for various applications, including textiles, plastics, and printing inks.

InChI:InChI=1/C8H8ClNO/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4H,1H3,(H2,10,11)

Upstream product

• 7664-93-9 sulfuric acid 
• 21423-81-4 3-chloro-4-methylbenzonitrile 
• 39652-32-9 (3-chloro-4-methylphenyl) methanol 
• 95-74-9 3-chloro-p-toluidine 

Downstream Products

• 3932-97-6 4-bromomethyl-3-chloro-benzamide 

Relevant academic research and scientific papers

Piperidine compound and preparation method and medical application thereof

The invention discloses a piperidine compound shown as a formula (I) and a preparation method and medical application thereof, and particularly relates to a piperidine USP7 inhibitor compound or pharmaceutically acceptable salt or ester or solvate thereof and a preparation method and application of the piperidine USP7 inhibitor compound or pharmaceutically acceptable salt or ester or solvate thereof. The compound provided by the invention can inhibit the activity of USP7 enzyme, has very good selectivity and druggability, and can be used for preparing medicines for preventing or treating tumor diseases or virus infectious diseases.

Atomically Dispersed Ru on Manganese Oxide Catalyst Boosts Oxidative Cyanation

There is a strong incentive for environmentally benign and sustainable production of organic nitriles to avoid the use of toxic cyanides. Here we report that manganese oxide nanorod-supported single-site Ru catalysts are active, selective, and stable for oxidative cyanation of various alcohols to give the corresponding nitriles with molecular oxygen and ammonia as the reactants. The very low amount of Ru (0.1 wt %) with atomic dispersion boosts the catalytic performance of manganese oxides. Experimental and theoretical results show how the Ru sites enhance the ammonia resistance of the catalyst, bolstering its performance in alcohol dehydrogenation and oxygen activation, the key steps in the oxidative cyanation. This investigation demonstrates the high efficiency of a single-site Ru catalyst for nitrile production.

A heterogeneous catalytic method for the conversion of nitriles into amides using molecular sieves modified with copper(II)

A heterogenous catalytic method is developed for the hydration of nitriles into amides with acetaldoxime. Copper(II) supported on 4 molecular sieves is an efficient catalyst for this reaction.

One-pot synthesis of symmetrical 1,3-diarylureas or substituted benzamides directly from benzylic primary alcohols and effective oxidation of secondary alcohols to ketones using phenyliodine diacetate in combination with sodium azide

Benzylic primary alcohols can be directly converted into symmetrical 1,3-diarylureas or substituted benzamides via an one-pot oxidative reaction using the combined reagent of phenyliodine diacetate and sodium azide. This new reaction constitutes a step-economical way to prepare symmetric 1,3-diarylureas or substituted benzamides depending upon the substituents on the phenyl rings of starting alcohols. The sodium acetate generated in situ from the ligand exchange between phenyliodine diacetate and sodium azide plays the pivotal role in the formation of 1,3-diarylureas. In addition, it is also found that various secondary alcohols can be readily oxidized to their corresponding ketones in excellent yields using the same reagent system of phenyliodine diacetate and sodium azide. Generally, secondary alcohols are preferentially oxidized to the corresponding ketones in the presence of primary ones with the limited amounts of phenyliodine diacetate and sodium azide.