24393-43-9

Basic information

• Product Name: 2-Propenoic acid, 3-(2-chlorophenyl)-2-cyano-, ethyl ester, (E)-
• CAS NO: 24393-43-9
• Molecular Formula: C12H10ClNO2
• Molecular Weight: 235.67
• Mol File: 24393-43-9.mol
• Article Data: 73

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(2-chlorophenyl)-2-cyano-, ethyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(2-chlorophenyl)-2-cyano-, ethyl ester, (E)-(24393-43-9)
• EPA Substance Registry System: 2-Propenoic acid, 3-(2-chlorophenyl)-2-cyano-, ethyl ester, (E)-(24393-43-9)

Safety Data

• Hazardous Substances Data: 24393-43-9(Hazardous Substances Data)

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 64-17-5 ethanol 
• 107-91-5 cyanoacetic acid amide 
• 70380-66-4 2-chlorobenzaldehyde dimethyl acetal 
• 89-97-4 2-CHLOROBENZYLAMINE 

Downstream Products

• 88148-60-1 ethyl 4-(2-chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyridine-2-carboxylate 
• 77198-25-5 2-Amino-6-(2-chloro-phenyl)-1,3-dicyano-4-p-tolyl-cyclohexa-2,4-dienecarboxylic acid ethyl ester 
• 129115-59-9 C₁₇H₁₂ClN₃O₂ 
• 89-98-5 2-chloro-benzaldehyde 
• 489414-14-4 5-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-3-(4-methyl-benzyl)-thiazolidine-2,4-dione 
• 55042-90-5 5-(2-chlorophenyl)-1-phenyl-1H-pyrazole 
• 111861-49-5 ethyl 3-amino-1-(2-chlorophenyl)-1H-benzo[f]chromene-2-carboxylate 

Relevant articles and documents

Imidazolium chloride immobilized SBA-15 as a heterogenized organocatalyst for solvent free Knoevenagel condensation using microwave

Heterogeneous organocatalyst, 1-methyl-3-[(3-triethoxysilyl) propyl] imidazolium chloride [MTESPImCl] immobilized SBA-15 (ILS) was synthesized by co-condensation method using microwave irradiation in which 1-methylimidazole (Im) was modified by organosila

Highly active zinc oxide-supported lithium oxide catalyst for solvent-free Knoevenagel condensation

Li2O/ZnO catalyst was prepared by wet impregnation method and characterized by XRD, SEM, EDX, FTIR, BET surface area and UV-Vis diffuse reflectance spectroscopy. This study revealed a decrease in average particle size and change in the shape of

Water mediated procedure for preparation of stereoselective oximes as inhibitors of MRCK kinase

Stereoselective aldoximes, preferably Z form have been obtained from α-cyano substituted carbonyl conjugated alkenes. This reaction occurs through Michael addition type reaction followed by retro-Knoevenagel reaction without transition-metal catalysis via C–C bond cleavage. These oximes are evaluated against cancer cell lines employing mechanistic study. Two oximes showed significant cytotoxic activity, which through in silico studies were found to inhibit MRCK Kinase, responsible for metastatic spread of cancer mortality.