244033-26-9

Upstream product

• 76-83-5 trityl chloride 
• 124-20-9 N-(3-aminopropyl)-1,4-diaminobutane 
• 110-57-6 trans-1,4-dichlorobut-2-ene 
• 244033-13-4 N^α,N^ω-ditritylspermidine 

Relevant academic research and scientific papers

Synthesis of spermidine and norspermidine dimers as high affinity polyamine transport inhibitors

A series of novel spermidine and sym-norspermidine dimers was synthesized by crosslinking the polyamine backbones via alkylation of their secondary amino groups to butyl, trans-2-butenyl, 2-butynyl or pxylyl bridges. The resulting hexamines behaved as high-affinity antagonists of polyamine uptake, with a relative potency that was dependent on the geometry of the linker structure.