244127-47-7

Upstream product

• 29274-13-3 5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 33149-25-6 7-chloro-5-phenyl-4H-pyrazolo[1,5-a]pyrimidine 
• 133690-92-3 [(2'-cyanobiphenyl-4-yl)methyl]amine 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship of a new series of potent angiotensin II receptor antagonists: Pyrazolo[1,5-α]pyrimidine derivatives

We have already reported 7-oxo-4,7-dihydropyrazolo[1,5-α]pyrimidine-3- carboxylic acid derivatives, which are potent in vitro angiotensin II (AII) antagonists, but have no oral antihypertensive activity. Removal of the carboxylic acid and replacement of t