24417-01-4Relevant academic research and scientific papers
Mild and efficient method for regioselective ring opening of aziridines with amines by bismuth trichloride
Swamy, Navath Raghavendra,Venkateswarlu
, p. 547 - 554 (2007/10/03)
Aziridines undergo the facile ring opening with anilines to afford the 1,2-diamines in excellent yields by bismuth trichloride in acetonitrile at ambient temperature.
Ring-opening reactions of nonactivated aziridines catalyzed by tris(pentafluorophenyl)borane
Watson, Iain D. G.,Yudin, Andrei K.
, p. 5160 - 5167 (2007/10/03)
The ring-opening reactions of nonactivated aziridines with amine nucleophiles are efficiently catalyzed by tris(pentafluorophenyl)borane leading to derivatives of trans-1,2-diamines in high yields. A mechanistic investigation of the reaction suggests that in situ formed [(C6F5)3B(OH2)]· H2O catalyzes the opening through a Bronsted acid manifold.
Preparation of trans-1,2-diaminocyclohexane derivatives by lithium perchlorate catalyzed ring opening of aziridines
De Parrodi,Vazquez,Quintero,Juaristi
, p. 3295 - 3302 (2007/10/03)
N,N′-Dialkylated trans-1,2-diaminocyclohexane derivatives were synthesized with good overall yield via reaction of the corresponding N-alkylated cyclohexene aziridine with amines, in the presence of lithium perchlorate as catalyst.
An intramolecular [2 + 3] cycloaddition route to fused 5-heterosubstituted tetrazoles
Demko, Zachary P.,Sharpless, K. Barry
, p. 4091 - 4094 (2007/10/03)
(matrix presented) Fused 5-heterotetrazole ring systems are synthesized in high yield via intramolecular [2 + 3] cycloadditions of organic azides and heteroatom-substituted nitriles. Cyanates, thiocyanates, and cyanamides are all competent dipolarophiles for this reaction. A variety of scaffolds are tolerated when the new enclosed ring is five- or six-membered.
