244183-00-4

Upstream product

• 161693-64-7 (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl chloroformate 
• 126378-42-5 4-methoxy-3-(trisopropylsilyl)pyridine 
• 38769-92-5 4-methoxybenzylmagnesium chloride 

Downstream Products

• 67009-58-9 (+)-metazocine 
• 244183-25-3 (2S,4S)-2-(4-methoxybenzyl)-1-methyl-4-piperidinol 
• 244183-15-1 (2S,4R)-2-(4-methoxybenzyl)-1-methyl-4-piperidinol 
• 244183-14-0 (2S)-2-(4-methoxybenzyl)-1-[(phenyloxy)carbonyl]-4-piperidone 
• 36402-80-9 C₁₅H₂₁NO 
• 244183-10-6 C₂₂H₂₇NO₄ 
• 244183-08-2 (2S,3S)-2-(4-methoxybenzyl)-3-methyl-1-[(phenyloxy)carbonyl]-4-piperidone 
• 244183-06-0 (2S,3S)-2-(4-methoxybenzyl)-3-methyl-1-[(phenyloxy)carbonyl]-2,3-dihydro-4-pyridone 
• 244183-02-6 (2S)-2-(4-methoxybenzyl)-2,3-dihydro-4-pyridone 

Relevant academic research and scientific papers

Synthetic studies toward (-)-FR901483 using a conjugate allylation to install the C-1 quaternary carbon

(Chemical Equation Presented) Two approaches to the aza-tricyclo dodecane skeleton of (-)-FR901483 are reported. Both routes utilized a Grignard addition to an N-acylpyridinium salt to establish the absolute stereochemistry at C-6 and a highly diastereose

Enantiopure n-acyldihydropyridones as synthetic intermediates: Asymmetric synthesis of benzomorphans

(Matrix presented) Concise asymmetric syntheses of several benzomorphan derivatives have been accomplished using enantiopure 2,3-dihydro-4-pyridones as chiral building blocks.